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局部麻醉药对大鼠和龟小肠钙转运的影响。

The effect of local anesthetics on calcium transport across the rat and turtle small intestine.

作者信息

Nassar C F, Haddad M E

出版信息

Comp Biochem Physiol A Comp Physiol. 1984;79(3):335-8. doi: 10.1016/0300-9629(84)90522-x.

DOI:10.1016/0300-9629(84)90522-x
PMID:6149841
Abstract

Procaine at different concentrations enhanced significantly (P less than 0.01) calcium accumulation in rat intestinal cells, whereas the same concentrations of procaine inhibited significantly (P less than 0.01) calcium uptake by the turtle small intestine. Unidirectional calcium influx across the rat small intestine was significantly enhanced (P less than 0.001) by the presence of procaine in the preincubation medium. However, procaine had no effect on calcium influx across the turtle intestinal cells. The cell water content and the cell volume were not altered by preincubating the intestinal tissues with procaine in both animals.

摘要

不同浓度的普鲁卡因显著增强(P<0.01)大鼠肠细胞中的钙积累,而相同浓度的普鲁卡因则显著抑制(P<0.01)龟小肠对钙的摄取。预孵育培养基中存在普鲁卡因时,大鼠小肠的单向钙内流显著增强(P<0.001)。然而,普鲁卡因对龟肠细胞的钙内流没有影响。用普鲁卡因预孵育两种动物的肠组织,细胞含水量和细胞体积均未改变。

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