Nartey Yvonne, Hill Philip C, Amo-Antwi Kwabena, Nyarko Kofi M, Yarney Joel, Cox Brian
*Hugh Adam Cancer Epidemiology Unit and †Centre for International Health, University of Otago, Dunedin, New Zealand; and ‡Department of Obstetrics and Gynecology, Komfo Anokye Teaching Hospital, Kumasi; and §Disease Control and Prevention Department, Ghana Health Service; and ∥National Centre for Radiotherapy and Nuclear Medicine, Korle Bu Teaching Hospital, Accra, Ghana.
Int J Gynecol Cancer. 2017 Nov;27(9):1926-1934. doi: 10.1097/IGC.0000000000001088.
: Cervical cancer is one of the most common cancers among women worldwide, and more than 85% of the disease occurs in low- and middle-income countries. Although it ranks as the most common cancer in Ghanaian women, there are no data available on cervical cancer survival.
Information on women with a diagnosis of cervical cancer from 2010 to 2013 was collected from the Komfo Anokye and Korle-Bu Teaching Hospitals through review of paper-based and electronic medical records (including pathology records) at the oncology units and the departments of obstetrics and gynecology. Telephone interviews were conducted with patients and relatives to gather further information. Data were recorded using a standardized questionnaire and analyzed using summary statistics.
Information for 821 women was available for the survival analysis. Of these, 497 (60.5%) died during follow-up. At 3 years after diagnosis, survival was 39%. Survival was lowest in women with stage IV disease. Women with squamous cell carcinoma had a survival advantage over those with adenocarcinoma. Furthermore, women who received surgery, radiotherapy, and chemotherapy had better survival than did women with other forms of treatment.
In conclusion, cervical cancer survival is low in Ghana and is likely to be improved if a greater proportion of the disease is detected early. Improving knowledge of the disease for early diagnosis, reducing financial barriers, and greater organization of health care delivery are likely to improve survival from cervical cancer in Ghana.
宫颈癌是全球女性中最常见的癌症之一，超过85%的病例发生在低收入和中等收入国家。尽管宫颈癌是加纳女性中最常见的癌症，但尚无宫颈癌生存率的数据。
通过查阅肿瘤科室以及妇产科的纸质和电子病历（包括病理记录），从Komfo Anokye和Korle-Bu教学医院收集2010年至2013年被诊断为宫颈癌的女性的信息。对患者及其亲属进行电话访谈以收集更多信息。使用标准化问卷记录数据并采用汇总统计进行分析。
821名女性的信息可用于生存分析。其中，497名（60.5%）在随访期间死亡。诊断后3年的生存率为39%。IV期疾病女性的生存率最低。鳞状细胞癌女性的生存率高于腺癌女性。此外，接受手术、放疗和化疗的女性比接受其他治疗方式的女性生存率更高。
总之，加纳宫颈癌的生存率较低，如果能早期发现更大比例的病例，生存率可能会提高。提高对该疾病的认识以进行早期诊断、减少经济障碍以及更好地组织医疗服务可能会提高加纳宫颈癌的生存率。
