IgA 肾病的黏膜皮质类固醇治疗。
Mucosal corticosteroid therapy of IgA nephropathy.
机构信息
Division of Nephrology and Immunology, RWTH University of Aachen, Aachen, Germany.
出版信息
Kidney Int. 2017 Aug;92(2):278-280. doi: 10.1016/j.kint.2017.05.021.
PMID:28709593
Abstract
The value of systemic immunosuppressive therapy for IgA nephropathy is uncertain. A recently completed randomized controlled phase II trial demonstrates that specially encapsulated budesonide, released preferentially in the terminal ileum, can reduce proteinuria and stabilize glomerular filtration rate in patients with IgA nephropathy.
摘要
IgA 肾病的全身性免疫抑制治疗的价值尚不确定。最近完成的一项随机对照 II 期临床试验表明，在回肠末端优先释放的特殊包被布地奈德可减少 IgA 肾病患者的蛋白尿并稳定肾小球滤过率。
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