Dev Tanvi, Thami Tarkik, Longchar Moanaro, Sethuraman Gomathy
Department of Dermatology , All India Institute of Medical Sciences, New Delhi, India.
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
BMJ Case Rep. 2017 Jul 14;2017:bcr-2017-221118. doi: 10.1136/bcr-2017-221118.
Facial granulomatous papules are important to recognise, as some of them are associated with significant systemic association, particularly sarcoidosis and certain infectious conditions. Lupus miliaris disseminatus faciei (LMDF) is a benign granulomatous disorder of unknown aetiology characterised by symmetrical, monomorphic, reddish-brown papules on the face. It is not associated with any underlying systemic involvement. We report a case of LMDF in a middle-aged man who presented to us with multiple asymptomatic and monomorphic reddish papules on the face for 3 months. Skin biopsy showed well-formed perifollicular epithelioid cell granulomas with focus of necrosis suggestive of LMDF. The lesions significantly responded to oral steroids.
面部肉芽肿性丘疹很重要,因为其中一些与严重的全身性关联有关,尤其是结节病和某些感染性疾病。面部播散性粟粒性狼疮(LMDF)是一种病因不明的良性肉芽肿性疾病,其特征为面部出现对称、单一形态的红棕色丘疹。它与任何潜在的全身性受累无关。我们报告一例中年男性的LMDF病例,该患者面部出现多个无症状、单一形态的红色丘疹达3个月。皮肤活检显示形成良好的毛囊周围上皮样细胞肉芽肿,并伴有坏死灶,提示为LMDF。这些皮损对口服类固醇有显著反应。