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限制性裸支架预防 B 型主动脉夹层血管内修复中远端支架移植物导致的新破口。

Restrictive bare stent prevents distal stent graft-induced new entry in endovascular repair of type B aortic dissection.

机构信息

Vascular Surgery Department, The First Affiliated Hospital, Sun Yat-sen University, Guangdong, China.

Vascular Surgery Department, The Third Affiliated Hospital, Sun Yat-sen University, Guangdong, China.

出版信息

J Vasc Surg. 2018 Jan;67(1):93-103. doi: 10.1016/j.jvs.2017.04.066. Epub 2017 Jul 13.

Abstract

OBJECTIVE

Distal stent graft-induced new entry (SINE) can occur after thoracic endovascular aortic repair (TEVAR) of type B aortic dissection. This study investigated the mechanism of distal SINE and its prevention using a restrictive bare stent (RBS) technique.

METHODS

From January 2013 to December 2014, 68 consecutive type B aortic dissection patients received endovascular repair at our center. The RBS technique was used with distal oversizing (between the diameter of the thoracic stent graft and the descending aorta true lumen diameter at the level of the intended distal edge of the thoracic stent graft) >20%.

RESULTS

Twenty-three patients received TEVAR with a single thoracic stent graft (TEVAR group, n = 23); the rest received TEVAR combined with the RBS technique (TEVAR + RBS group, n = 45). Four distal SINEs occurred in the TEVAR group. Distal oversizing (69.7% ± 35.5% vs 31.2% ± 24.5%; P = .005) and expansion mismatch ratio (132.2% ± 16.9% vs 106.5% ± 11.6%; P < .05) were significantly higher in the SINE patients. Compared with standard TEVAR, TEVAR + RBS was associated with significantly lower distal oversizing (TEVAR vs TEVAR + RBS group, 59.8% ± 24.7% vs 16.7% ± 7.6%; P < .05), lower expansion mismatch ratio (113.8% ± 14.6% vs 103.8% ± 11.7%; P = .012), and lower distal SINE rate (4/23 [17.4%] vs 0/45 [0%]; P = .011). Compared with the TEVAR group, the false lumen was reduced significantly at the level of the RBS distal edge (P = .029).

CONCLUSIONS

Excessive distal oversizing and distal expansion mismatch ratio may contribute to the occurrence of distal SINE. The RBS technique reduced the incidence of distal SINE. Based on our midterm and long-term observations, implantation of an RBS may improve aortic remodeling.

摘要

目的

胸主动脉腔内修复术(TEVAR)治疗 B 型主动脉夹层后可发生远端支架移植物内新入口(SINE)。本研究采用限制性裸支架(RBS)技术探讨远端 SINE 的发生机制及其预防方法。

方法

2013 年 1 月至 2014 年 12 月,我院对 68 例连续的 B 型主动脉夹层患者进行了血管内修复。使用远端过度扩张(胸支架移植物直径与胸支架移植物远端边缘水平降主动脉真腔直径之间的直径比>20%)>20%的 RBS 技术。

结果

23 例患者接受了单一胸支架移植物 TEVAR(TEVAR 组,n=23);其余患者接受了 TEVAR 联合 RBS 技术(TEVAR+RBS 组,n=45)。TEVAR 组有 4 例发生远端 SINE。SINE 患者的远端过度扩张(69.7%±35.5%比 31.2%±24.5%;P=0.005)和扩张不匹配率(132.2%±16.9%比 106.5%±11.6%;P<0.05)明显更高。与标准 TEVAR 相比,TEVAR+RBS 与远端过度扩张(TEVAR 与 TEVAR+RBS 组,59.8%±24.7%比 16.7%±7.6%;P<0.05)、扩张不匹配率(113.8%±14.6%比 103.8%±11.7%;P=0.012)和远端 SINE 发生率(4/23[17.4%]比 0/45[0%];P=0.011)显著降低有关。与 TEVAR 组相比,RBS 远端边缘水平的假腔明显减少(P=0.029)。

结论

远端过度扩张和远端扩张不匹配率可能导致远端 SINE 的发生。RBS 技术降低了远端 SINE 的发生率。基于我们的中期和长期观察,植入 RBS 可能改善主动脉重塑。

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