1 Hospital Universitario de Bellvitge, Universidad de Barcelona, Spain.
2 Sociedad Española de Cardiología, Guadalupe, Madrid, Spain.
Eur Heart J Acute Cardiovasc Care. 2019 Apr;8(3):242-251. doi: 10.1177/2048872617719651. Epub 2017 Jul 17.
We aimed to assess the impact of implementation of reperfusion networks, the type of hospital and specialty of the treating physician on the management and outcomes of ST segment elevation myocardial infarction in patients aged ⩾75 years.
We analysed data from the Minimum Basic Data Set of the Spanish public health system, assessing hospital discharges between 2004 and 2013. Discharges were distributed in three groups depending on the clinical management: percutaneous coronary intervention, thrombolysis or no reperfusion. Primary outcome measure was all cause in-hospital mortality. For risk adjustment, patient comorbidities were identified for each index hospitalization.
We identified 299,929 discharges, of whom 107,890 (36%) were in-patients aged ⩾75 years. Older patients had higher prevalence of comorbidities, were less often treated in high complexity hospitals and were less frequently managed by cardiologists ( p<0.001). Both percutaneous coronary intervention and fibrinolysis were less often performed in elderly patients ( p<0.001). A progressive increase in the rate of percutaneous coronary intervention was observed in the elderly across the study period (from 17% in 2004 to 45% in 2013, p<0.001), with a progressive reduction of crude mortality (from 23% in 2004 to 19% in 2013, p<0.001). Adjusted analysis showed an association between being treated in high complexity hospitals, being treated by cardiologists and lower in-hospital mortality ( p <0.001).
Elderly patients with ST segment elevation myocardial infarction are less often managed in high complexity hospitals and less often treated by cardiologists. Both factors are associated with higher in-hospital mortality.
本研究旨在评估再灌注网络的实施、医院类型和治疗医生的专业对 ⩾75 岁 ST 段抬高型心肌梗死患者的管理和结局的影响。
我们分析了西班牙公共卫生系统的最低基本数据集的数据,评估了 2004 年至 2013 年期间的医院出院情况。根据临床管理将出院患者分为三组:经皮冠状动脉介入治疗、溶栓或无再灌注。主要结局指标为全因院内死亡率。为了风险调整,为每个索引住院确定了患者的合并症。
我们确定了 299929 例出院患者,其中 107890 例(36%)为 ⩾75 岁的住院患者。老年患者合并症的患病率更高,在高复杂医院治疗的比例较低,接受心脏病专家治疗的比例也较低( p<0.001)。老年患者接受经皮冠状动脉介入治疗和溶栓治疗的比例较低( p<0.001)。在研究期间,老年患者接受经皮冠状动脉介入治疗的比例呈逐渐上升趋势(从 2004 年的 17%上升到 2013 年的 45%, p<0.001),粗死亡率呈逐渐下降趋势(从 2004 年的 23%下降到 2013 年的 19%, p<0.001)。调整分析显示,在高复杂医院接受治疗、由心脏病专家治疗与较低的院内死亡率相关( p <0.001)。
⩾75 岁 ST 段抬高型心肌梗死患者在高复杂医院接受治疗的比例较低,接受心脏病专家治疗的比例也较低。这两个因素均与较高的院内死亡率相关。