Jung Hahn Jin, Wee Jee Hye, Rhee Chae-Seo, Kim Jeong-Whun
Department of Otorhinolaryngology-Head and Neck Surgery, Chungbuk National University College of Medicine, Chungbuk National University Hospital, Cheongju, South Korea.
Department of Otorhinolaryngology, Bundang Jesaeng General Hospital, Deajin Medical Center, Seongnam, South Korea.
Laryngoscope. 2017 Dec;127(12):2897-2902. doi: 10.1002/lary.26740. Epub 2017 Jul 17.
OBJECTIVES/HYPOTHESIS: To determine the average proportion of retropalatal or retroglossal obstruction occurring during a whole night in single patients with obstructive sleep apnea.
Retrospective analysis.
Patients who underwent full-night polysomnography and upper airway pressure manometry at the same time were retrospectively enrolled. Airway obstruction levels were categorized into retropalatal or retroglossal obstruction according to the pressure change shown during pressure manometry. The proportion of retropalatal/retroglossal obstruction was calculated for each patient. Independent factors associated with the proportion were assessed.
A total of 218 patients (198 men) with obstructive sleep apnea were included in the study (mean age, 46.8 ± 1.6 years; body mass index, 26.7 ± 3.1 kg/m ). The average proportion of retroglossal and retropalatal obstruction in individuals was 36.2% and 63.8%, respectively. The apnea-hypopnea index was not significantly correlated with the proportion of retroglossal obstruction (P = .219) after adjustment for age, sex, and body mass index. Meanwhile, the proportion of retroglossal obstruction was significantly correlated with oxygen desaturation index (P = .036), average oxygen saturation (P = .006), lowest oxygen saturation (P = .028), and time below 90% oxygen saturation (P = .021).
To our knowledge, this is the first study showing the average proportions of retropalatal/retroglossal obstruction occurring in single individuals with obstructive sleep apnea during a whole night. The proportion of upper airway obstruction site was significantly associated with oxygen desaturation.
目的/假设：确定阻塞性睡眠呼吸暂停单例患者整个夜间发生腭后或舌后阻塞的平均比例。
回顾性分析。
回顾性纳入同时接受全夜多导睡眠图和上气道压力测量的患者。根据压力测量期间显示的压力变化，将气道阻塞水平分为腭后或舌后阻塞。计算每位患者腭后/舌后阻塞的比例。评估与该比例相关的独立因素。
本研究共纳入218例阻塞性睡眠呼吸暂停患者（198例男性）（平均年龄46.8±1.6岁；体重指数26.7±3.1kg/m²）。个体中舌后和腭后阻塞的平均比例分别为36.2%和63.8%。在对年龄、性别和体重指数进行调整后，呼吸暂停低通气指数与舌后阻塞比例无显著相关性（P = 0.219）。同时，舌后阻塞比例与氧饱和度下降指数（P = 0.036）、平均氧饱和度（P = 0.006）、最低氧饱和度（P = 0.028）以及低于90%氧饱和度的时间（P = 0.021）显著相关。
据我们所知，这是第一项显示阻塞性睡眠呼吸暂停单例患者整个夜间发生腭后/舌后阻塞平均比例的研究。上气道阻塞部位的比例与氧饱和度下降显著相关。
4。《喉镜》，2017年，第127卷，第2897 - 2902页。
