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用于评估超声热暴露的磁共振成像兼容型乳房/肋骨模型

MRI-compatible breast/rib phantom for evaluating ultrasonic thermal exposures.

作者信息

Menikou Georgios, Yiannakou Marinos, Yiallouras Christos, Ioannides Cleanthis, Damianou Christakis

机构信息

City University, London, UK.

Cyprus University of Technology, Limassol, Cyprus.

出版信息

Int J Med Robot. 2018 Feb;14(1). doi: 10.1002/rcs.1849. Epub 2017 Jul 17.

Abstract

INTRODUCTION

The target of this study was the development of a magnetic resonance imaging (MRI) compatible breast phantom for focused ultrasound which includes plastic (ABS) ribs. The objective of the current study was the evaluation of a focused ultrasound procedure using the proposed phantom that eliminates rib heating.

MATERIAL AND METHODS

The proposed phantom was evaluated using two different focused ultrasound exposures. The surrounding breast tissue was mimicked using an agar-silica-evaporation milk gel (2% w/v - 2% w/v - 40% v/v).

RESULTS

The attenuation of the ABS was similar to that of ribs. MR thermometry of focused ultrasound exposures were acquired using the breast/rib phantom. In one exposure focused ultrasound was applied with far-field targeting of the ribs. In the other exposure, the transducer was positioned laterally, thus avoiding exposure of the rib to focused ultrasound.

CONCLUSIONS

Due to growing interest in using MRI guided focused ultrasound (MRgFUS) for patients with breast cancer, the proposed breast/rib phantom can be utilized as a very useful tool for evaluating ultrasonic protocols.

摘要

引言

本研究的目标是开发一种用于聚焦超声的磁共振成像(MRI)兼容乳腺体模,该体模包含塑料(ABS)肋骨。本研究的目的是评估使用所提出的体模进行的聚焦超声程序,该程序可消除肋骨发热。

材料与方法

使用两种不同的聚焦超声暴露对所提出的体模进行评估。使用琼脂-二氧化硅-蒸发乳凝胶(2% w/v - 2% w/v - 40% v/v)模拟周围乳腺组织。

结果

ABS的衰减与肋骨相似。使用乳腺/肋骨体模获取聚焦超声暴露的磁共振温度测量结果。在一次暴露中,对肋骨进行远场靶向施加聚焦超声。在另一次暴露中,将换能器横向定位,从而避免肋骨暴露于聚焦超声。

结论

由于对使用MRI引导聚焦超声(MRgFUS)治疗乳腺癌患者的兴趣日益增加,所提出的乳腺/肋骨体模可作为评估超声方案的非常有用的工具。

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