Gaab M R, Ungersböck K, Hufenbeck B
Neurol Res. 1986 Mar;8(1):44-52. doi: 10.1080/01616412.1986.11739730.
The recording of intracranial pressure (ICP) is increasingly performed routinely in the hospital setting. Documentation of the pressure course over long time intervals has been performed, until recently, with paper tracings. Objective means of evaluation are lacking, however, for the quantification of pressure-dynamics. We have therefore tested several different statistical and graphical methods of evaluation to improve the efficacy of ICP monitoring. Calculations were done on epidural and transfontanel pressure monitoring. Analyses were performed both on-line and off-line. Graphical methods used included time-plot graphs, histograms, correlations analysis and pulse-amplitude/mean pressure diagrams (PA/Pm); statistical values calculated included mean, variance, standard deviation, coefficient of skewness, coefficient of kurtosis, coefficient of variation and the range. Data obtained from patients with normal intracranial pressure, CSF circulatory disturbances, head injuries, cerebrovascular disorders, and other illnesses allowed for the clear establishment of normal ICP limits, the rapid recognition of pathological pressure changes, the evaluation of therapeutic effects, and also an improvement in the comparability between new measurements and previous recordings. Simultaneously performed on-line evaluation of ICP recordings proved to be a practical means of monitoring both baseline values and therapeutic effectiveness.
在医院环境中，颅内压（ICP）监测越来越常规化。直到最近，长时间颅内压变化过程的记录一直通过纸质记录来完成。然而，目前缺乏用于量化压力动态变化的客观评估方法。因此，我们测试了几种不同的统计和图形评估方法，以提高ICP监测的效能。对硬膜外和经囟门压力监测数据进行了计算，并进行了在线和离线分析。使用的图形方法包括时间曲线图、直方图、相关性分析以及脉搏振幅/平均压力图（PA/Pm）；计算的统计值包括均值、方差、标准差、偏度系数、峰度系数、变异系数和极差。从颅内压正常、脑脊液循环障碍、头部损伤、脑血管疾病及其他疾病患者获得的数据，有助于明确建立正常ICP范围，快速识别病理性压力变化，评估治疗效果，还能提高新测量值与先前记录之间的可比性。同时进行的ICP记录在线评估被证明是监测基线值和治疗效果的一种实用方法。
