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经口内镜甲状腺切除术前庭入路(TOETVA):适应证、技术和结果。

Transoral endoscopic thyroidectomy vestibular approach (TOETVA): indications, techniques and results.

机构信息

Minimally-Invasive and Endocrine Surgery Division, Department of Surgery, Police General Hospital, 492/1 Rama I Road, Pathumwan, Bangkok, 10330, Thailand.

Department of Surgery, KUMC Thyroid Center, Korea University Hospital, Korea University College of Medicine, Seoul, South Korea.

出版信息

Surg Endosc. 2018 Jan;32(1):456-465. doi: 10.1007/s00464-017-5705-8. Epub 2017 Jul 17.

Abstract

INTRODUCTION

The Transoral Neck Surgery (TONS) Study Group was established at the 1st International Thyroid NOTES Conference in February 2016 with the intention of standardizing and refining thyroid NOTES techniques, including both transoral endoscopic and robotic thyroidectomy approaches. Herein, the authors report the modification of indications, preparation, and step-by-step explanations for operative techniques, as well as results and postoperative care for transoral endoscopic thyroidectomy vestibular approach (TOETVA).

METHODS

Between February 2015 and December 2015, a total of 200 patients comprising 8 males (4%) and 192 females (96%) underwent TOETVA using 3 laparoscopic ports inserted at the oral vestibule. Of these patients, 111 presented with single thyroid nodules (55.5%), while 66 patients had multinodular goiters (33%), 12 had Graves' disease (6%) and 11 had papillary microcarcinoma (5.5%). The CO insufflation pressure was maintained at 6 mmHg. Each surgery was performed using laparoscopic instruments and ultrasonic devices.

RESULTS

TOETVA was performed on 200 consecutive patients. No conversion to conventional open surgery was necessary. Average tumor size was 4.1 ± 1.78 cm (1-10 cm). Median operative time was 97 ± 40.5 min (45-300 min). Median blood loss was 30 ± 46.25 mL (6-300 mL). Mean visual analog scale measurements were 2.41 ± 2.04 (2-7), 1.17 ± 1.4 (0-5), and 0.47 ± 0.83 (0-3) on the first, second, and third days, respectively. Temporary hoarseness and hypoparathyroidism occurred in 8 patients (4%) and 35 patients (17.5%), respectively. No permanent hoarseness or hypoparathyroidism occurred. Mental nerve injury occurred in 3 patients (1.5%). One patient (0.5%) developed a post-operative hematoma that required open surgery. No infection was identified.

CONCLUSION

TOETVA was shown to be safe and feasible with a reasonable surgical duration and minimal pain scores. This approach shows promise for those patients who are motivated to avoid a neck scar.

摘要

介绍

经口颈部手术(TONS)研究小组于 2016 年 2 月在第一届国际甲状腺NOTES 会议上成立,旨在标准化和完善甲状腺NOTES 技术,包括经口内镜和机器人甲状腺切除术方法。在此,作者报告了经口内镜甲状腺切除术前庭入路(TOETVA)的适应证、准备和手术技术的逐步解释的修改,以及手术结果和术后护理。

方法

2015 年 2 月至 2015 年 12 月,共 200 例患者(8 例男性(4%)和 192 例女性(96%))采用 3 个腹腔镜端口经口腔前庭行 TOETVA 治疗。这些患者中,111 例为单发甲状腺结节(55.5%),66 例为多结节性甲状腺肿(33%),12 例为 Graves 病(6%),11 例为甲状腺微小乳头状癌(5.5%)。CO 充气压力维持在 6mmHg。每例手术均使用腹腔镜器械和超声设备进行。

结果

TOETVA 连续应用于 200 例患者,无一例转为常规开放性手术。肿瘤平均大小为 4.1±1.78cm(1-10cm)。中位手术时间为 97±40.5min(45-300min)。中位出血量为 30±46.25ml(6-300ml)。术后第 1、2、3 天的平均视觉模拟量表评分分别为 2.41±2.04(2-7)、1.17±1.4(0-5)和 0.47±0.83(0-3)。8 例(4%)患者出现暂时性声音嘶哑和甲状旁腺功能减退,35 例(17.5%)患者出现暂时性声音嘶哑和甲状旁腺功能减退。无永久性声音嘶哑或甲状旁腺功能减退。3 例(1.5%)患者出现精神神经损伤。1 例(0.5%)患者术后发生血肿,需行开放性手术。无感染发生。

结论

TOETVA 具有安全可行的特点,手术时间合理,疼痛评分低。这种方法对于那些希望避免颈部疤痕的患者有一定的应用前景。

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