Division of thyroid Surgery, China-Japan Union Hospital Of Jilin University, Jilin Provincial Key Laboratory Of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, 126 Xiantai Blvd, Changchun, Jilin, P.R. China.
Division for Endocrine Surgery, Department of Human Pathology in Adulthood and Childhood ''G. Barresi'', University Hospital G. Martino, University of Messina, Via C. Valeria 1, 98125, Messina, Italy.
J Endocrinol Invest. 2019 Nov;42(11):1345-1351. doi: 10.1007/s40618-019-01071-0. Epub 2019 Jun 11.
Knowledge of visual analog scale (VAS) pain assessment for transoral endoscopic thyroidectomy vestibular approach (TOETVA) is limited. The purpose of this analysis was to classify the postoperative discomfort scores in patients undergoing TOETVA compared to open thyroidectomy.
Observational clinical study of patients who underwent thyroidectomy by VAS pain assessment from September 2016 to March 2017. Patients were stratified into two groups: patients eligible for TOETVA (Group TOETVA) and non-candidates for endoscopic intervention (open thyroidectomy approach-OTA). VAS was recorded in the recovery room, at 24 h, + 2, + 5, + 15, + 30, + 90 days, and 6 months after surgery. Pain assessment was stratified in VAS-lower lip, VAS-chin, VAS-jaw, VAS-anterior neck, VAS-cervical/back, VAS-swallowing, VAS-brushing, VAS-speaking, and VAS-shaving. Secondary outcome assessed were analgesic rescue dose, morbidity, operative notes, hospital stay, and histopathology.
41 TOETVA and 45 OTA constituted the analysis. There were differences between the TOETVA and OTA for age, gland volume, mean nodule diameter, coexistence thyroiditis, bilateral procedures, and use of drain. Operative time was longer in TOETVA. Results indicated that TOETVA was associated with reduced neck, cervical back, and swallowing VAS scores in the 24 h after surgery. Conversely, jaw and brushing teeth resulted in higher VAS score in TOETVA group. OTA patients never experienced lower lip or chin pain. The use of rescue analgesics did not differ between the two groups.
VAS was used to measure treatment outcome in TOETVA. VAS scores achieved overall a minimal clinical importance difference from the two procedures. There appears to be both a short- and long-term different range of interpretations of pain between TOETVA and OTA.
经口内镜甲状腺切除术(TOETVA)前庭入路的视觉模拟量表(VAS)疼痛评估知识有限。本分析的目的是比较 TOETVA 与开放性甲状腺切除术患者术后不适评分。
对 2016 年 9 月至 2017 年 3 月间接受 VAS 疼痛评估的甲状腺切除术患者进行观察性临床研究。患者分为两组:TOETVA 组(TOETVA 组)和内镜干预非候选组(开放式甲状腺切除术入路-OTA 组)。VAS 在恢复室、术后 24 小时、+2、+5、+15、+30、+90 天和 6 个月时记录。疼痛评估分为下唇 VAS、颏部 VAS、下颌 VAS、颈前 VAS、颈后/背部 VAS、吞咽 VAS、刷牙 VAS、说话 VAS 和剃须 VAS。次要结局评估为镇痛解救剂量、发病率、手术记录、住院时间和组织病理学。
41 例 TOETVA 和 45 例 OTA 构成了分析。TOETVA 组和 OTA 组在年龄、腺体体积、结节平均直径、共存甲状腺炎、双侧手术和引流管使用方面存在差异。TOETVA 的手术时间较长。结果表明,TOETVA 术后 24 小时颈、颈后和吞咽 VAS 评分较低。相反,TOETVA 组下颌和刷牙的 VAS 评分较高。OTA 患者从未出现下唇或颏部疼痛。两组之间使用解救镇痛药物无差异。
VAS 用于评估 TOETVA 的治疗效果。两种手术 VAS 评分总体上达到了最小临床重要差异。TOETVA 和 OTA 之间似乎存在短期和长期不同的疼痛范围解释。