Lin Wei-Chieh, Ye Ciou-Nan, Lin Chung-Ching, Jitpratoom Pornpeera, Wu Hung-Pin, Chou Yi-Fan
Department of Otolaryngology, Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.
School of Medicine, Tzu Chi University, Hualien, Taiwan.
Tzu Chi Med J. 2024 Aug 19;37(1):86-90. doi: 10.4103/tcmj.tcmj_41_24. eCollection 2025 Jan-Mar.
The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a minimally invasive technique. This study aimed to compare the safety of TOETVA with fibrin sealant (Tisseel) and TOETVA with drainage.
Patients who underwent TOETVA between January 2018 and December 2021 were divided into drainage ( = 20) and Tisseel ( = 30) groups.
The primary outcome was the incidence of complications. The secondary outcomes were operative time and postoperative pain. There were no significant differences in patient demographics, tumor size, intraoperative blood loss, and hospitalization days between the two groups. No patient required conversion to open thyroidectomy. The incidence of complications and postoperative pain was similar in the two groups. The operative time for TOETVA with Tisseel was significantly shorter than for TOETVA with drainage ( = 0.038).
TOETVA with Tisseel is a safe alternative to TOETVA with drainage, having a short operative time.
经口内镜甲状腺切除术前庭入路（TOETVA）是一种微创技术。本研究旨在比较使用纤维蛋白密封剂（Tisseel）的TOETVA和带引流的TOETVA的安全性。
将2018年1月至2021年12月期间接受TOETVA的患者分为引流组（n = 20）和Tisseel组（n = 30）。
主要结局是并发症的发生率。次要结局是手术时间和术后疼痛。两组患者的人口统计学特征、肿瘤大小、术中出血量和住院天数无显著差异。无患者需要转为开放性甲状腺切除术。两组并发症发生率和术后疼痛相似。使用Tisseel的TOETVA手术时间明显短于带引流的TOETVA（P = 0.038）。
使用Tisseel的TOETVA是带引流的TOETVA的一种安全替代方法，手术时间短。
