Dharmarajan Kumar, Wang Yongfei, Lin Zhenqiu, Normand Sharon-Lise T, Ross Joseph S, Horwitz Leora I, Desai Nihar R, Suter Lisa G, Drye Elizabeth E, Bernheim Susannah M, Krumholz Harlan M
Center for Outcomes Research and Evaluation, Yale New Haven Health, New Haven, Connecticut2Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut3Now with Clover Health, Jersey City, New Jersey.
Center for Outcomes Research and Evaluation, Yale New Haven Health, New Haven, Connecticut2Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
JAMA. 2017 Jul 18;318(3):270-278. doi: 10.1001/jama.2017.8444.
The Affordable Care Act has led to US national reductions in hospital 30-day readmission rates for heart failure (HF), acute myocardial infarction (AMI), and pneumonia. Whether readmission reductions have had the unintended consequence of increasing mortality after hospitalization is unknown.
To examine the correlation of paired trends in hospital 30-day readmission rates and hospital 30-day mortality rates after discharge.
DESIGN, SETTING, AND PARTICIPANTS: Retrospective study of Medicare fee-for-service beneficiaries aged 65 years or older hospitalized with HF, AMI, or pneumonia from January 1, 2008, through December 31, 2014.
Thirty-day risk-adjusted readmission rate (RARR).
Thirty-day RARRs and 30-day risk-adjusted mortality rates (RAMRs) after discharge were calculated for each condition in each month at each hospital in 2008 through 2014. Monthly trends in each hospital's 30-day RARRs and 30-day RAMRs after discharge were examined for each condition. The weighted Pearson correlation coefficient was calculated for hospitals' paired monthly trends in 30-day RARRs and 30-day RAMRs after discharge for each condition.
In 2008 through 2014, 2 962 554 hospitalizations for HF, 1 229 939 for AMI, and 2 544 530 for pneumonia were identified at 5016, 4772, and 5057 hospitals, respectively. In January 2008, mean hospital 30-day RARRs and 30-day RAMRs after discharge were 24.6% and 8.4% for HF, 19.3% and 7.6% for AMI, and 18.3% and 8.5% for pneumonia. Hospital 30-day RARRs declined in the aggregate across hospitals from 2008 through 2014; monthly changes in RARRs were -0.053% (95% CI, -0.055% to -0.051%) for HF, -0.044% (95% CI, -0.047% to -0.041%) for AMI, and -0.033% (95% CI, -0.035% to -0.031%) for pneumonia. In contrast, monthly aggregate changes across hospitals in hospital 30-day RAMRs after discharge varied by condition: HF, 0.008% (95% CI, 0.007% to 0.010%); AMI, -0.003% (95% CI, -0.005% to -0.001%); and pneumonia, 0.001% (95% CI, -0.001% to 0.003%). However, correlation coefficients in hospitals' paired monthly changes in 30-day RARRs and 30-day RAMRs after discharge were weakly positive: HF, 0.066 (95% CI, 0.036 to 0.096); AMI, 0.067 (95% CI, 0.027 to 0.106); and pneumonia, 0.108 (95% CI, 0.079 to 0.137). Findings were similar in secondary analyses, including with alternate definitions of hospital mortality.
Among Medicare fee-for-service beneficiaries hospitalized for heart failure, acute myocardial infarction, or pneumonia, reductions in hospital 30-day readmission rates were weakly but significantly correlated with reductions in hospital 30-day mortality rates after discharge. These findings do not support increasing postdischarge mortality related to reducing hospital readmissions.
《平价医疗法案》已使美国全国范围内心力衰竭(HF)、急性心肌梗死(AMI)和肺炎的医院30天再入院率降低。再入院率降低是否会导致住院后死亡率上升这一意外后果尚不清楚。
研究出院后医院30天再入院率与30天死亡率的配对趋势之间的相关性。
设计、地点和参与者:对2008年1月1日至2014年12月31日因HF、AMI或肺炎住院的65岁及以上医疗保险按服务收费受益人的回顾性研究。
30天风险调整再入院率(RARR)。
计算2008年至2014年各医院每月每种疾病出院后的30天RARR和30天风险调整死亡率(RAMR)。检查各医院每种疾病出院后30天RARR和30天RAMR的月度趋势。计算各医院每种疾病出院后30天RARR和30天RAMR配对月度趋势的加权Pearson相关系数。
2008年至2014年,分别在5016家、4772家和5057家医院确定了2962554例HF住院病例、1229939例AMI住院病例和2544530例肺炎住院病例。2008年1月,HF出院后的平均医院30天RARR和30天RAMR分别为24.6%和8.4%,AMI为19.3%和7.6%,肺炎为18.3%和8.5%。2008年至2014年,各医院的医院30天RARR总体呈下降趋势;HF的RARR月度变化为-0.053%(95%CI,-0.055%至-0.051%),AMI为-0.044%(95%CI,-0.047%至-0.041%),肺炎为-0.033%(95%CI,-0.035%至-0.031%)。相比之下,各医院出院后30天RAMR的月度总体变化因疾病而异:HF为0.008%(95%CI,0.007%至0.010%);AMI为-0.003%(95%CI,-0.005%至-0.001%);肺炎为0.001%(95%CI,-0.001%至0.003%)。然而,各医院出院后30天RARR和30天RAMR配对月度变化的相关系数呈弱正相关:HF为0.066(95%CI,0.036至0.096);AMI为0.067(95%CI,0.027至0.106);肺炎为0.108(95%CI,0.079至0.137)。在包括医院死亡率替代定义的二次分析中,结果相似。
在因心力衰竭、急性心肌梗死或肺炎住院的医疗保险按服务收费受益人中,医院30天再入院率的降低与出院后30天死亡率的降低呈弱但显著的相关性。这些发现不支持因减少医院再入院而导致出院后死亡率增加。