掌骨巨细胞瘤：病例报告
Giant Cell Tumor of the Metacarpal: Case Report.
作者信息
Lewallen Laura W, Wagner Eric R, Moran Steven L
机构信息
1 Mayo Clinic, Rochester, MN, USA.
出版信息
Hand (N Y). 2017 Sep;12(5):NP113-NP117. doi: 10.1177/1558944717697431. Epub 2017 Mar 7.
BACKGROUND
Giant cell tumor (GCT) of bone is a benign, though locally aggressive tumor, classically described as an eccentric lytic lesion, often with cortical expansion and destruction. It typically involves the metaphysis or epiphysis of long bones in skeletally mature patients, with a slight female predominance. The incidence in the small bones of the hand has been reported to be 2% to 5%.
METHODS
Treatment options have evolved in recent years, and currently include intralesional curettage with or without adjuvant therapy, wide resection, and occasionally amputation.
RESULTS
In this report, we present a long-term follow-up (10 years) of a patient with GCT involving a metacarpal, who was initially reconstructed with a metacarpal head allograft, which was eventually revised to a metacarpophalangeal (MCP) total joint arthroplasty.
CONCLUSIONS
To our knowledge, this is the only report of pyrocarbon being used for tumor reconstruction and the only report of late MCP allograft salvage.
背景
骨巨细胞瘤（GCT）是一种良性但具有局部侵袭性的肿瘤，传统上被描述为偏心性溶骨性病变，常伴有皮质膨胀和破坏。它通常累及骨骼成熟患者长骨的干骺端或骨骺，女性略占优势。据报道，手部小骨的发病率为2%至5%。
方法
近年来治疗方案不断发展，目前包括病灶内刮除术（有无辅助治疗）、广泛切除术，偶尔也会进行截肢术。
结果
在本报告中，我们展示了一名掌骨骨巨细胞瘤患者的长期随访（10年）情况，该患者最初采用掌骨头同种异体骨移植进行重建，最终改为掌指（MCP）全关节置换术。
结论
据我们所知，这是唯一一篇关于热解碳用于肿瘤重建的报告，也是唯一一篇关于晚期MCP同种异体骨挽救的报告。
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