Bouassida Mouna, Fourati Nada, Krichen Fatma, Zouari Raida, Ellouz-Chaabouni Semia, Ghribi Dhouha
University of Sfax, ENIS, Unit of Enzymes and Bioconcersion, Road Soukra km 4, 3038 Sfax, Tunisia.
University of Sfax, ISBS, Higher Institute of Biotechnology of Sfax, Road Soukra km 4, 3038 Sfax, Tunisia.
J Adv Res. 2017 Jul;8(4):425-433. doi: 10.1016/j.jare.2017.04.002. Epub 2017 Apr 19.
Toothpaste is a gel dentifrice used with a toothbrush as an accessory to clean, keep and promote oral hygiene. The literature review suggests that there are many different formulations of toothpastes and that each of their individual components present specific functions. The concentration of the toothpaste ingredients must be appropriately chosen taking into account the purposes of the toothpaste. Biosurfactants are considered as suitable molecules for application in many formulations such as in toothpaste one. In the present work, two dentifrice formulations were investigated and their efficiencies were tested using chemical surfactant agent and lipopeptide biosurfactant isolated from SPB1. The physicochemical properties were analyzed considering several tests mainly spreading ability, water activity, pH, foaming and cleaning tests. The obtained results indicated that the SPB1 biosurfactant was as efficient as the chemical surfactant confirming its potential utilization in toothpaste formulation compared to the commercial one. The evaluation of the antimicrobial activity of the formulated dentifrice was carried out against eight bacteria. The results demonstrated that the biosurfactant-based product exhibited an important antimicrobial activity, which was very effective against
牙膏是一种凝胶状洁齿剂，与牙刷配套使用，用于清洁、保持和促进口腔卫生。文献综述表明，牙膏有许多不同的配方，其每种成分都有特定的功能。必须根据牙膏的用途适当选择牙膏成分的浓度。生物表面活性剂被认为是适用于许多配方的分子，比如牙膏配方。在本研究中，对两种洁齿剂配方进行了研究，并使用化学表面活性剂和从SPB1分离的脂肽生物表面活性剂测试了它们的功效。通过几项测试分析了其理化性质，主要包括铺展能力、水分活度、pH值、发泡和清洁测试。所得结果表明，SPB1生物表面活性剂与化学表面活性剂一样有效，证实了其与市售产品相比在牙膏配方中的潜在用途。对配制的洁齿剂针对八种细菌进行了抗菌活性评估。结果表明，基于生物表面活性剂的产品表现出重要的抗菌活性，对……非常有效
