Roszell D K, Calsyn D A
Int J Addict. 1986 Feb;21(2):175-90. doi: 10.3109/10826088609063448.
This study reviews the prescription of psychoactive medications in a methadone maintenance clinic and looks for salient personality and cognitive differences between medication groups based on the administration of a battery of psychological tests. One hundred and nine consecutive admissions to a methadone program were studied, of which 38.5% had received a psychoactive medication in addition to methadone. The data were analyzed comparing results for antianxiety and antidepressant medication groups as well as a methadone-only group. The antianxiety medication group displayed more somatic complaints, worries, and tension and was more timid, impulsive, and pessimistic than the other two groups. There were only small differences between the antidepressant medication and methadone-only groups. There were no significant differences between groups on cognitive measures. Meaningful differences in several demographic variables also emerged. The implications for this research are discussed.
本研究回顾了美沙酮维持治疗门诊中精神活性药物的处方情况，并通过一系列心理测试，寻找用药组之间显著的人格和认知差异。对连续109例进入美沙酮治疗项目的患者进行了研究，其中38.5%的患者除美沙酮外还接受了精神活性药物治疗。分析数据时比较了抗焦虑和抗抑郁药物治疗组以及仅使用美沙酮组的结果。抗焦虑药物治疗组比其他两组表现出更多的躯体不适、担忧和紧张情绪，且更胆小、冲动和悲观。抗抑郁药物治疗组和仅使用美沙酮组之间只有微小差异。各组在认知指标上没有显著差异。几个人口统计学变量也出现了有意义的差异。讨论了本研究的意义。
