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减肥手术与强化生活方式及药物干预治疗2型糖尿病的成本及医疗保健利用影响

Cost and Health Care Utilization Implications of Bariatric Surgery Versus Intensive Lifestyle and Medical Intervention for Type 2 Diabetes.

作者信息

Banerjee Souvik, Garrison Louis P, Flum David R, Arterburn David E

机构信息

Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.

Department of Pharmacy, University of Washington, Seattle, Washington, USA.

出版信息

Obesity (Silver Spring). 2017 Sep;25(9):1499-1508. doi: 10.1002/oby.21927. Epub 2017 Jul 19.

Abstract

OBJECTIVE

The aim of this study was to compare the cost and health care utilization of patients with obesity and type 2 diabetes mellitus (T2DM) randomized into either Roux-en-Y gastric bypass (RYGB) surgery or an intensive lifestyle and medical intervention (ILMI).

METHODS

This analysis (N = 745) is based on 2-year follow-up of a small randomized controlled trial (RCT); adult patients with obesity and T2DM were recruited between 2011 and 2012 from Kaiser Permanente Washington. Comparisons were made for patients randomized into either RYGB (N = 15) or ILMI (N = 17).

RESULTS

There were no significant cost savings for RYGB versus ILMI patients through the follow-up years. Pharmacy cost was lower for RYGB versus ILMI patients by about $900 in year 2 versus year 0; however, inpatient and emergency room costs were higher for surgery patients in follow-up years relative to year 0. Median total cost for nonrandomized patients was higher in year 0 and in year 2 compared to randomized patients.

CONCLUSIONS

Bariatric surgery is not cost saving in the short term. Moreover, the costs of patients who enter into RCTs of RYGB may differ from the costs of those who do not enter RCTs, suggesting use of caution when using such data to draw inferences about the general population with obesity.

摘要

目的

本研究旨在比较接受Roux-en-Y胃旁路术(RYGB)或强化生活方式与药物干预(ILMI)的肥胖合并2型糖尿病(T2DM)患者的成本和医疗保健利用情况。

方法

本分析(N = 745)基于一项小型随机对照试验(RCT)的2年随访;2011年至2012年期间从华盛顿凯撒医疗集团招募了肥胖合并T2DM的成年患者。对随机分为RYGB组(N = 15)或ILMI组(N = 17)的患者进行了比较。

结果

在随访期间,RYGB组患者与ILMI组患者相比没有显著的成本节约。与ILMI组患者相比,RYGB组患者在第2年的药房成本比第0年降低了约900美元;然而,随访期间手术患者的住院和急诊室成本相对于第0年更高。未随机分组患者在第0年和第2年的总费用中位数高于随机分组患者。

结论

短期内减肥手术并不能节省成本。此外,进入RYGB随机对照试验的患者成本可能与未进入随机对照试验的患者成本不同,这表明在使用此类数据推断肥胖普通人群时应谨慎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4384/5769931/3782913dd709/nihms929851f1.jpg

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