芬太尼和阿芬太尼对静脉诱导药物睡眠时间影响的比较。
A comparison of the effects of fentanyl and alfentanil on the sleeping times of the intravenous induction agents.
作者信息
Dingwall A E, Pleuvry B J
出版信息
J Pharm Pharmacol. 1986 Apr;38(4):323-5. doi: 10.1111/j.2042-7158.1986.tb04579.x.
Abstract
The effect of increasing doses of fentanyl and alfentanil administered before four intravenous induction agents (thiopentone, methohexitone, Althesin and etomidate) on the sleeping time were studied in mice. A biphasic pattern of sleeping time was noted with the more rapidly metabolized and eliminated compounds. Possible explanations are discussed.
摘要
研究了在四种静脉诱导剂（硫喷妥钠、甲己炔巴比妥、阿耳忒辛和依托咪酯）之前给予递增剂量的芬太尼和阿芬太尼对小鼠睡眠时间的影响。对于代谢和消除较快的化合物，观察到睡眠时间呈双相模式。文中讨论了可能的解释。
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