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急性心肌梗死住院期间的手持式超声心动图检查。

Handheld echocardiography during hospitalization for acute myocardial infarction.

作者信息

Cullen Michael W, Geske Jeffrey B, Anavekar Nandan S, Askew J Wells, Lewis Bradley R, Oh Jae K

机构信息

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.

出版信息

Clin Cardiol. 2017 Nov;40(11):993-999. doi: 10.1002/clc.22754. Epub 2017 Jul 19.

Abstract

BACKGROUND

Handheld echocardiography (HHE) is concordant with standard transthoracic echocardiography (TTE) in a variety of settings but has not been thoroughly compared to traditional TTE in patients with acute myocardial infarction (AMI).

HYPOTHESIS

Completed by experienced operators, HHE provides accurate diagnostic capabilities compared with standard TTE in AMI patients.

METHODS

This study prospectively enrolled patients admitted to the coronary care unit with AMI. Experienced sonographers performed HHE with a V-scan. All patients underwent clinical TTE. Each HHE was interpreted by 2 experts blinded to standard TTE. Agreement was assessed with κ statistics and concordance correlation coefficients.

RESULTS

Analysis included 82 patients (mean age, 66 years; 74% male). On standard TTE, mean left ventricular (LV) ejection fraction was 46%. Correlation coefficients between HHE and TTE were 0.75 (95% confidence interval: 0.66 to 0.82) for LV ejection fraction and 0.69 (95% confidence interval: 0.58 to 0.77) for wall motion score index. The κ statistics ranged from 0.47 to 0.56 for LV enlargement, 0.55 to 0.79 for mitral regurgitation, and 0.44 to 0.57 for inferior vena cava dilatation. The κ statistics were highest for the anterior (0.81) and septal (0.71) apex and lowest for the mid inferolateral (0.36) and basal inferoseptal (0.36) walls.

CONCLUSIONS

In patients with AMI, HHE and standard TTE demonstrate good correlation for LV function and wall motion. Agreement was less robust for structural abnormalities and specific wall segments. In experienced hands, HHE can provide a focused assessment of LV function in patients hospitalized with AMI; however, HHE should not substitute for comprehensive TTE.

摘要

背景

手持式超声心动图(HHE)在多种情况下与标准经胸超声心动图(TTE)结果一致,但在急性心肌梗死(AMI)患者中尚未与传统TTE进行全面比较。

假设

由经验丰富的操作人员完成的HHE与标准TTE相比,在AMI患者中具有准确的诊断能力。

方法

本研究前瞻性纳入入住冠心病监护病房的AMI患者。经验丰富的超声检查人员使用V型扫描进行HHE检查。所有患者均接受临床TTE检查。每位HHE检查结果由2名对标准TTE结果不知情的专家解读。采用κ统计量和一致性相关系数评估一致性。

结果

分析纳入82例患者(平均年龄66岁;74%为男性)。在标准TTE检查中,左心室(LV)平均射血分数为46%。HHE与TTE之间的相关系数,LV射血分数为0.75(95%置信区间:0.66至0.82),壁运动评分指数为0.69(95%置信区间:0.58至0.77)。LV扩大的κ统计量范围为0.47至0.56,二尖瓣反流为0.55至0.79,下腔静脉扩张为0.44至0.57。κ统计量在前壁(0.81)和室间隔(0.71)心尖处最高,在中下外侧壁(0.36)和基底室间隔壁(0.36)处最低。

结论

在AMI患者中,HHE与标准TTE在LV功能和壁运动方面显示出良好的相关性。在结构异常和特定壁段方面,一致性较差。在经验丰富的人员操作下,HHE可为住院的AMI患者提供LV功能的重点评估;然而,HHE不应替代全面的TTE检查。

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