圈养食蟹猴群体的遗传特征分析（ ）。 需注意，原文括号内内容缺失，以上翻译根据现有内容给出。
Genetic Characterization of a Captive Colony of Pigtailed Macaques ().
作者信息
Zhang Xinjun, Kanthaswamy Sree, Trask Jessica S, Ng Jillian, Oldt Robert F, Mankowski Joseph L, Adams Robert J, Smith David G
机构信息
Department of Anthropology and California National Primate Research Center, University of California Davis, Davis, California.
School of Mathematical and Natural Sciences, Arizona State University, Glendale, Arizona.
出版信息
J Am Assoc Lab Anim Sci. 2017 Jul 1;56(4):390-395.
Effective colony management is critical to guarantee the availability of captive NHP as subjects for biomedical research. Pigtailed macaques (Macaca nemestrina) are an important model for the study of human and nonhuman primate diseases and behavior. Johns Hopkins University hosts one of the largest captive colonies of pigtailed macaques in the United States. In this study, we used 56 single-nucleotide polymorphisms (SNP) to characterize this population of pigtailed macaques, understand their population structure, and assess the effectiveness of their colony management. The results demonstrate that the colony has maintained a high level of genetic diversity, with no loss of heterozygosity since its origin, and low levels of inbreeding and genetic subdivision.
有效的群体管理对于确保圈养非人灵长类动物作为生物医学研究对象的可用性至关重要。豚尾猕猴（食蟹猴）是研究人类和非人类灵长类疾病及行为的重要模型。约翰·霍普金斯大学拥有美国最大的豚尾猕猴圈养群体之一。在本研究中，我们使用了56个单核苷酸多态性（SNP）来表征这群豚尾猕猴，了解它们的种群结构，并评估其群体管理的有效性。结果表明，该群体保持了高水平的遗传多样性，自起源以来杂合性没有丧失，近亲繁殖和遗传细分水平较低。
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