Division of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Am J Gastroenterol. 2017 Jul;112(7):1056-1060. doi: 10.1038/ajg.2017.117.
Endoscopic surveillance in Barrett's esophagus (BE) has numerous limitations and thus provides several opportunities for improving the effectiveness of our current surveillance strategies. Several risk stratification and prediction tools have been investigated to identify patients at highest risk for progression to esophageal adenocarcinoma (EAC). Persistence of non-dysplastic BE (NDBE) has been proposed as an indicator of lower risk of progression to EAC. This editorial highlights the variable results and methodologies in studies evaluating persistence of NDBE as a risk stratification tool in the surveillance of BE patients and provides guidance for optimizing outcomes in BE patients enrolled in surveillance programs.
内镜监测在 Barrett 食管（BE）中存在诸多局限性，因此为提高我们当前监测策略的有效性提供了多个机会。已经研究了几种风险分层和预测工具，以确定进展为食管腺癌（EAC）风险最高的患者。非异型增生性 BE（NDBE）的持续存在被提出作为进展为 EAC 的风险较低的指标。本社论强调了评估 NDBE 持续性作为 BE 患者监测中风险分层工具的研究中的可变结果和方法，并为优化纳入监测计划的 BE 患者的结果提供了指导。
