印度北方邦戈勒克布尔地区，恙虫病作为急性脑炎综合征的病因
Scrub Typhus as a Cause of Acute Encephalitis Syndrome, Gorakhpur, Uttar Pradesh, India.
作者信息
Mittal Mahima, Thangaraj Jeromie Wesley Vivian, Rose Winsley, Verghese Valsan Philip, Kumar C P Girish, Mittal Mahim, Sabarinathan R, Bondre Vijay, Gupta Nivedita, Murhekar Manoj V
出版信息
Emerg Infect Dis. 2017 Aug;23(8):1414-1416. doi: 10.3201/eid2308.170025.
Abstract
Outbreaks of acute encephalitis syndrome (AES) have been occurring in Gorakhpur Division, Uttar Pradesh, India, for several years. In 2016, we conducted a case-control study. Our findings revealed a high proportion of AES cases with Orientia tsutsugamushi IgM and IgG, indicating that scrub typhus is a cause of AES.
摘要
印度北方邦戈勒克布尔分区多年来一直在爆发急性脑炎综合征（AES）。2016年，我们开展了一项病例对照研究。我们的研究结果显示，急性脑炎综合征病例中恙虫病东方体IgM和IgG比例很高，这表明恙虫病是急性脑炎综合征的一个病因。
相似文献
1
Scrub Typhus as a Cause of Acute Encephalitis Syndrome, Gorakhpur, Uttar Pradesh, India.
Emerg Infect Dis. 2017 Aug;23(8):1414-1416. doi: 10.3201/eid2308.170025.
2
Occurrence of Orientia tsutsugamushi, the Etiological Agent of Scrub Typhus in Animal Hosts and Mite Vectors in Areas Reporting Human Cases of Acute Encephalitis Syndrome in the Gorakhpur Region of Uttar Pradesh, India.
Vector Borne Zoonotic Dis. 2018 Oct;18(10):539-547. doi: 10.1089/vbz.2017.2246. Epub 2018 Jul 17.
3
Acute Encephalitis Syndrome in Eastern Uttar Pradesh, India: Changing Etiological Understanding.
J Med Entomol. 2018 May 4;55(3):523-526. doi: 10.1093/jme/tjy042.
4
Investigations of seasonal outbreaks of acute encephalitis syndrome due to in Gorakhpur region, India: A One Health case study.
Indian J Med Res. 2021 Mar;153(3):375-381. doi: 10.4103/ijmr.IJMR_625_21.
5
Seroprevalence & seroincidence of infection in Gorakhpur, Uttar Pradesh, India: A community-based serosurvey during lean (April-May) & epidemic (October-November) periods for acute encephalitis syndrome.
Indian J Med Res. 2020 Apr;151(4):350-360. doi: 10.4103/ijmr.IJMR_1330_18.
6
Scrub Typhus Leading to Acute Encephalitis Syndrome, Assam, India.
Emerg Infect Dis. 2017 Jan;23(1):148-150. doi: 10.3201/eid2301.161038. Epub 2017 Jan 15.
7
Scrub Typhus as an Etiology of Acute Febrile Illness in Gorakhpur, Uttar Pradesh, India, 2016.
Am J Trop Med Hyg. 2017 Nov;97(5):1313-1315. doi: 10.4269/ajtmh.17-0135. Epub 2017 Aug 18.
8
Association of Scrub Typhus in Children with Acute Encephalitis Syndrome and Meningoencephalitis, Southern India.
Emerg Infect Dis. 2023 Apr;29(4):711-722. doi: 10.3201/eid2904.221157.
9
Seasonal abundance of Leptotrombidium deliense, the vector of scrub typhus, in areas reporting acute encephalitis syndrome in Gorakhpur district, Uttar Pradesh, India.
Exp Appl Acarol. 2021 Aug;84(4):795-808. doi: 10.1007/s10493-021-00650-2. Epub 2021 Jul 30.
10
Risk Factors for Acquiring Scrub Typhus among Children in Deoria and Gorakhpur Districts, Uttar Pradesh, India, 2017.
Emerg Infect Dis. 2018 Dec;24(12):2364-2367. doi: 10.3201/eid2412.180695.
引用本文的文献
1
Seroprevalence of scrub typhus among patients with acute febrile illness: A study from northern districts of West Bengal.
J Family Med Prim Care. 2025 Jul;14(7):2768-2773. doi: 10.4103/jfmpc.jfmpc_1761_24. Epub 2025 Jul 21.
2
Role of Intravenous Azithromycin as Adjunctive Therapy in Children With Acute Encephalitis Syndrome (AES): An Open-Label Randomized Controlled Trial.
Cureus. 2025 Jul 6;17(7):e87387. doi: 10.7759/cureus.87387. eCollection 2025 Jul.
3
Microbial Spectrum of Acute Encephalitis Syndrome With Special Reference to Non-Japanese Encephalitis Cases.
Cureus. 2025 Jun 18;17(6):e86266. doi: 10.7759/cureus.86266. eCollection 2025 Jun.
4
Exploring OmpA of Orientia tsutsugamushi to design novel multi-epitope vaccine against scrub typhus: an immunoinformatics approach.
Mol Divers. 2025 Jul 9. doi: 10.1007/s11030-025-11236-0.
5
CRISPR/Cas12a-Based Detection Platform for Early and Rapid Diagnosis of Scrub Typhus.
Biosensors (Basel). 2023 Dec 8;13(12):1021. doi: 10.3390/bios13121021.
6
A Case Series of Scrub Meningoencephalitis from a Tertiary Care Center in North India.
Ann Indian Acad Neurol. 2023 Jul-Aug;26(4):549-552. doi: 10.4103/aian.aian_135_23. Epub 2023 Sep 11.
7
Scrub Typhus in Children: A Prospective Observational Study in a Tertiary Care Hospital in Eastern India.
Cureus. 2023 Jul 16;15(7):e41976. doi: 10.7759/cureus.41976. eCollection 2023 Jul.
8
Phylogenetic and immunological investigations of complete TSA56 ORF of Orientia tsutsugamushi present in acute encephalitis syndrome cases from eastern Uttar Pradesh, India.
Arch Microbiol. 2023 Apr 8;205(5):178. doi: 10.1007/s00203-023-03492-1.
9
Scrub typhus in urban areas of Wardha district in central India.
Indian J Med Res. 2022 Sep;156(3):435-441. doi: 10.4103/ijmr.IJMR_707_19.
10
Changing Spectrum of Acute Encephalitis Syndrome in India and a Syndromic Approach.
Ann Indian Acad Neurol. 2022 May-Jun;25(3):354-366. doi: 10.4103/aian.aian_1117_21. Epub 2022 Jun 8.
本文引用的文献
1
Acute encephalitis syndrome in Gorakhpur, Uttar Pradesh, India - Role of scrub typhus.
J Infect. 2016 Dec;73(6):623-626. doi: 10.1016/j.jinf.2016.08.014. Epub 2016 Sep 1.
2
Diagnostic Accuracy of the InBios Scrub Typhus Detect Enzyme-Linked Immunoassay for the Detection of IgM Antibodies in Northern Thailand.
Clin Vaccine Immunol. 2015 Dec 9;23(2):148-54. doi: 10.1128/CVI.00553-15. Print 2016 Feb.
3
Epidemiology and etiology of acute encephalitis syndrome in North India.
Jpn J Infect Dis. 2014;67(3):197-203. doi: 10.7883/yoken.67.197.
4
Changes in acute encephalitis syndrome incidence after introduction of Japanese encephalitis vaccine in a region of India.
J Infect. 2014 Aug;69(2):200-2. doi: 10.1016/j.jinf.2014.03.013. Epub 2014 Mar 20.
5
Changing landscape of acute encephalitis syndrome in India: a systematic review.
Natl Med J India. 2012 Jul-Aug;25(4):212-20.
6
Changing clinico-laboratory profile of encephalitis patients in the eastern Uttar Pradesh region of India.
Trop Doct. 2012 Apr;42(2):106-8. doi: 10.1258/td.2011.110391.
Zotero 插件