Suppr超能文献

钌(II)催化的取代芳烃、烯烃和杂芳烃与烯烃通过去质子化途径进行螯合辅助C-H烯基化反应的最新进展。

Recent advances in the ruthenium(ii)-catalyzed chelation-assisted C-H olefination of substituted aromatics, alkenes and heteroaromatics with alkenes via the deprotonation pathway.

作者信息

Manikandan Rajendran, Jeganmohan Masilamani

机构信息

Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021, India.

出版信息

Chem Commun (Camb). 2017 Aug 8;53(64):8931-8947. doi: 10.1039/c7cc03213g.

Abstract

The transition-metal-catalyzed chelation-assisted alkenylation at the inert C-H bond of aromatics with alkenes is one of the efficient methods to synthesize substituted vinylarenes in a highly regio- and stereoselective manner. Palladium, rhodium and ruthenium complexes are frequently used as catalysts for this type of transformation. The present review describes the recent advances in the ruthenium-catalyzed chelation-assisted alkenylation at the C-H bond of aromatics, alkenes and heteroaromatics with alkenes via the deprotonation pathway. Several directing groups including 2-pyridyl, carbonyl, amidine, amide, amine, imidate, sulphonic acid, triazole, cyano, oxazolidinone and hydontoin are widely used in the reaction. The scope, limitation and mechanistic investigation of the alkenylation reactions are discussed elaborately. This feature article includes all the reported ruthenium-catalyzed alkenylation reactions via the deprotonation pathway until the end of March 2017.

摘要

过渡金属催化的芳烃惰性C-H键与烯烃的螯合辅助烯基化反应,是以高区域选择性和立体选择性方式合成取代乙烯基芳烃的有效方法之一。钯、铑和钌配合物经常用作这类转化反应的催化剂。本综述描述了钌催化的芳烃、烯烃和杂芳烃的C-H键与烯烃通过去质子化途径进行螯合辅助烯基化反应的最新进展。包括2-吡啶基、羰基、脒、酰胺、胺、亚氨酸酯、磺酸、三唑、氰基、恶唑烷酮和乙内酰脲在内的几种导向基团在该反应中被广泛使用。本文详细讨论了烯基化反应的范围、局限性及机理研究。这篇专题文章涵盖了截至2017年3月底所有报道的通过去质子化途径进行的钌催化烯基化反应。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验