运动训练可改善小腹部主动脉瘤患者的通气效率：一项随机对照研究。
Exercise Training Improves Ventilatory Efficiency in Patients With a Small Abdominal Aortic Aneurysm: A RANDOMIZED CONTROLLED STUDY.
机构信息
Faculty of Physical Education, University of Brasília, Brasília, Brazil (Dr Lima); Division of Cardiology, Veterans Affairs Palo Alto Health Care System, Palo Alto, California (Drs Lima, Vainshelboim, Chan, and Myers, and Ms Ganatra); and Stanford University, Stanford, California (Drs Lima, Vainshelboim, Dalman, and Myers).
出版信息
J Cardiopulm Rehabil Prev. 2018 Jul;38(4):239-245. doi: 10.1097/HCR.0000000000000270.
PURPOSE
To investigate the effects of exercise training on ventilatory efficiency and physiological responses to submaximal exercise in subjects with small abdominal aortic aneurysm (AAA).
METHODS
Sixty-five male patients (72.3 ± 7.0 years) were randomized to exercise training (n = 33) or usual care group (n = 32). Exercise subjects participated in a training groups for 3 mo. Cardiopulmonary exercise testing was performed before and after the study period and peak (Equation is included in full-text article.)O2, the ventilatory threshold (VT), the oxygen uptake efficiency slope (OUES), and the (Equation is included in full-text article.)E2/(Equation is included in full-text article.)CO2 slope were identified. Baseline work rates at VT were matched to examine cardiopulmonary responses after training.
RESULTS
Significant interactions indicating improvements before and after training in the exercise group were noted for time (P < .01), (Equation is included in full-text article.)O2 (P < .01), and work rate (P < .01) at the VT. At peak effort, significant interactions were noted for time (P < .01) and work rate (P < .01), while borderline significance was noted for absolute (P = .07) and relative (P = .04) (Equation is included in full-text article.)O2. Significant interactions were observed for the OUES both when using all exercise data (P = .04) and when calculated up to the VT (P < .01). For the (Equation is included in full-text article.)E2/(Equation is included in full-text article.)CO2 slope, significance was noted only when calculated up to the VT (P = .04). After training, heart rate, (Equation is included in full-text article.)E, (Equation is included in full-text article.)O2 and respiratory exchange ratio were significantly attenuated for the same baseline work rate only in the exercise group (all P < .01).
CONCLUSIONS
Exercise training improves ventilatory efficiency in patients with small AAA. In addition, patients who exercised exhibited less demanding cardiorespiratory responses to submaximal effort.
目的
研究运动训练对小腹主动脉瘤（AAA）患者的通气效率和亚最大运动时生理反应的影响。
方法
将 65 名男性患者（72.3±7.0 岁）随机分为运动训练组（n=33）和常规护理组（n=32）。运动组参加了 3 个月的训练组。在研究前后进行心肺运动测试，并确定峰值（方程包含在全文文章中。）O2、通气阈（VT）、摄氧量效率斜率（OUES）和（方程包含在全文文章中。）E2/（方程包含在全文文章中。）CO2 斜率。在训练后检查 VT 时匹配基线工作率以检查心肺反应。
结果
运动组的时间（P<.01）、（方程包含在全文文章中。）O2（P<.01）和 VT 时的工作率（P<.01）均存在显著交互作用，提示训练前后均有改善。在峰值用力时，时间（P<.01）和工作率（P<.01）的交互作用显著，而绝对（P=.07）和相对（P=.04）（方程包含在全文文章中。）O2 接近边缘显著。当使用所有运动数据时（P=.04）和当计算到 VT 时（P<.01），OUES 均观察到显著的交互作用。对于（方程包含在全文文章中。）E2/（方程包含在全文文章中。）CO2 斜率，仅在计算到 VT 时（P=.04）才有意义。训练后，仅在运动组中，在相同的基线工作率下，心率、（方程包含在全文文章中。）E、（方程包含在全文文章中。）O2 和呼吸交换率均显著降低（均 P<.01）。
结论
运动训练可改善小 AAA 患者的通气效率。此外，运动的患者在亚最大运动时的心肺反应要求较低。
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