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中国老年人群的睡眠障碍与跌倒风险——如皋长寿与衰老研究

Sleep disturbances and risk of falls in an old Chinese population-Rugao Longevity and Ageing Study.

作者信息

Ma Teng, Shi Guoping, Zhu Yinsheng, Wang Yong, Chu Xuefeng, Jiang Xiaoyan, Liu Zuyun, Cai Jian, Wang Hongfei, Jin Li, Wang Zhendong, Wang Xiaofeng

机构信息

Unit of Epidemiology, MOE Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China.

Rugao People's Hospital, Rugao 226500, Jiangsu, China.

出版信息

Arch Gerontol Geriatr. 2017 Nov;73:8-14. doi: 10.1016/j.archger.2017.07.003. Epub 2017 Jul 12.

Abstract

BACKGROUND

To explore the relationship between sleep disturbances and falls in an elderly Chinese population.

METHODS

Data from 1726 individuals aged 70-87 years from the Rugao Longevity and Ageing Study were used. The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep variables. Outcomes were falls ≥1 time per year and falls ≥2 times per year.

RESULTS

A total of 22.7% of the participants experienced ≥1 fall, and 9.8% experienced ≥2 falls per year. Poor sleep quality was associated with ≥1 fall (OR 1.08, 95% CI 1.05-1.12; OR 1.27, 95% CI 1.14-1.41) and ≥2 falls (OR 1.08, 95% CI 1.03-1.14; OR 1.28, 95% CI 1.10-1.48), with an increase per PSQI score and SD PSQI score, respectively. In addition, sleep quality, sleep latency, sleep efficiency, and sleep disturbance subcomponents were associated with an increased risk of ≥1 fall with ORs of 1.44 (95% CI, 1.21-1.72), 1.23 (95%CI,1.09-1.40), 1.12 (95%CI, 1.01-1.23) and 1.70 (95% CI,1.35-2.14), respectively, and were associated with an increased risk of ≥2 falls with ORs 1.54 (95%CI, 1.22-1.96), 1.21(95%CI, 1.02-1.44), 1.17 (95% CI 1.02-1.33), and 1.78 (95%CI, 1.31-2.44), respectively. Further, participants slept ≤5h per night had an increased risk of ≥1 fall (OR 2.34; 95%CI, 1.59-3.46) and ≥2 falls (OR 2.19; 95%CI, 1.30-3.69).

CONCLUSIONS

Poor sleep quality and several subcomponent sleep symptoms were consistently associated with increased risk of falls ≥1 time and ≥2 times in Chinese elderly. The identification of sleep disturbances may help identify high-risk Chinese elders who may benefit from fall prevention education.

摘要

背景

探讨中国老年人群睡眠障碍与跌倒之间的关系。

方法

使用来自如皋长寿与衰老研究的1726名70 - 87岁个体的数据。采用匹兹堡睡眠质量指数(PSQI)评估睡眠变量。结局指标为每年跌倒≥1次和每年跌倒≥2次。

结果

共有22.7%的参与者经历过≥1次跌倒,9.8%的参与者每年经历≥2次跌倒。睡眠质量差与每年跌倒≥1次(比值比1.08,95%置信区间1.05 - 1.12;比值比1.27,95%置信区间1.14 - 1.41)和跌倒≥2次相关(比值比1.08,95%置信区间1.03 - 1.14;比值比1.28,95%置信区间1.10 - 1.48),分别随PSQI评分和PSQI标准差评分增加。此外,睡眠质量、入睡潜伏期、睡眠效率和睡眠障碍子成分与跌倒≥1次风险增加相关,比值比分别为1.44(95%置信区间1.21 - 1.72)、1.23(95%置信区间1.09 - 1.40)、1.12(95%置信区间1.01 - 1.23)和1.70(95%置信区间1.35 - 2.14),与跌倒≥2次风险增加相关,比值比分别为1.54(95%置信区间1.22 - 1.96)、1.21(95%置信区间1.02 - 1.44)、1.17(95%置信区间1.02 - 1.33)和1.78(95%置信区间1.31 - 2.44)。此外,每晚睡眠≤5小时的参与者跌倒≥1次(比值比2.34;95%置信区间1.59 - 3.46)和跌倒≥2次(比值比2.19;95%置信区间1.30 - 3.69)的风险增加。

结论

睡眠质量差和几种睡眠症状子成分与中国老年人跌倒≥1次和≥2次的风险增加始终相关。识别睡眠障碍可能有助于识别可能从预防跌倒教育中受益的高危中国老年人。

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