Department of Psychiatry, University of Milan, Fondazione IRCCS Ca'Granda, Ospedale Maggiore Policlinico, 20122 Milano, Italy; Department of Psychiatry and Behavioral Sciences, Stanford University, 94305 Stanford, CA, USA.
Department of Psychiatry, University of Milan, Fondazione IRCCS Ca'Granda, Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Eur Psychiatry. 2017 Sep;45:36-40. doi: 10.1016/j.eurpsy.2017.06.008. Epub 2017 Jul 4.
Obsessive-compulsive disorder (OCD) is a highly disabling condition, with frequent early onset. Adult/adolescent OCD has been extensively investigated, but little is known about prevalence and clinical characterization of geriatric patients with OCD (G-OCD≥65years). The present study aimed to assess prevalence of G-OCD and associated socio-demographic and clinical correlates in a large international sample.
Data from 416 outpatients, participating in the ICOCS network, were assessed and categorized into 2 groups, age<vs≥65years, and then divided on the basis of the median age of the sample (age<vs≥42years). Socio-demographic and clinical variables were compared between groups (Pearson Chi-squared and t tests).
G-OCD compared with younger patients represented a significant minority of the sample (6% vs 94%, P<.001), showing a significantly later age at onset (29.4±15.1 vs 18.7±9.2years, P<.001), a more frequent adult onset (75% vs 41.1%, P<.001) and a less frequent use of cognitive-behavioural therapy (CBT) (20.8% vs 41.8%, P<.05). Female gender was more represented in G-OCD patients, though not at a statistically significant level (75% vs 56.4%, P=.07). When the whole sample was divided on the basis of the median age, previous results were confirmed for older patients, including a significantly higher presence of women (52.1% vs 63.1%, P<.05).
G-OCD compared with younger patients represented a small minority of the sample and showed later age at onset, more frequent adult onset and lower CBT use. Age at onset may influence course and overall management of OCD, with additional investigation needed.
强迫症(OCD)是一种高度致残的疾病,常发病于早期。成人/青少年 OCD 已得到广泛研究,但对于 OCD 老年患者(G-OCD≥65 岁)的患病率和临床特征知之甚少。本研究旨在评估大型国际样本中 G-OCD 的患病率及其相关的社会人口学和临床相关性。
评估了参加 ICOCS 网络的 416 名门诊患者的数据,并将其分为年龄<vs≥65 岁两组,然后根据样本的中位数年龄(年龄<vs≥42 岁)进一步分为两组。比较两组之间的社会人口学和临床变量(皮尔逊卡方检验和 t 检验)。
与年轻患者相比,G-OCD 仅占样本的一小部分(6% vs 94%,P<.001),发病年龄明显较晚(29.4±15.1 vs 18.7±9.2 岁,P<.001),成人发病更为常见(75% vs 41.1%,P<.001),认知行为疗法(CBT)的使用率较低(20.8% vs 41.8%,P<.05)。尽管在统计学上没有达到显著水平,但 G-OCD 患者中女性比例更高(75% vs 56.4%,P=.07)。当根据中位数年龄将整个样本分为两组时,上述结果在年龄较大的患者中得到了证实,包括女性的比例显著更高(52.1% vs 63.1%,P<.05)。
与年轻患者相比,G-OCD 仅占样本的一小部分,发病年龄较晚,成人发病更为常见,CBT 的使用率较低。发病年龄可能会影响 OCD 的病程和整体管理,需要进一步研究。