2019冠状病毒病大流行期间的强迫症——一项系统综述
Obsessive-Compulsive Disorder During the COVID-19 Pandemic-A Systematic Review.
作者信息
Linde Elisabeth S, Varga Tibor V, Clotworthy Amy
机构信息
Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
出版信息
Front Psychiatry. 2022 Mar 25;13:806872. doi: 10.3389/fpsyt.2022.806872. eCollection 2022.
BACKGROUND
The COVID-19 pandemic and its associated restrictions may contribute to a deterioration in mental health; individuals with obsessive-compulsive disorder (OCD) may be particularly affected. This systematic review aimed to investigate the effects of the current pandemic on people diagnosed with OCD, and whether pandemics may affect the development of OCD symptoms.
METHODS
We conducted a systematic search using NCBI PubMed, SCOPUS, and Google Scholar on February 9, 2021. Research articles related to OCD and COVID-19 or other pandemics were attempted to be identified using pre-defined search terms. Case reports, clinical guidelines, letters, and clinical research articles including ≥100 participants were included; reviews were excluded. The systematic review adheres to PRISMA guidelines and the Newcastle-Ottawa Scale was used to assess the quality of the included clinical research articles.
RESULTS
A total of 79 articles were included in the full-text assessment. Of these, 59 were clinical research articles, two were clinical guidelines, six were case reports, and 12 were letters. The research articles examined OCD symptoms in adult patients with diagnosed OCD, the general population, pregnant women, healthcare workers, students, and young adults, children, and adolescents. Only one study on OCD in previous pandemics was identified.
CONCLUSION
This systematic review found that people both with and without diagnosed OCD prior to the pandemic generally experienced a worsened landscape of symptoms of OCD during the COVID-19 pandemic. However, the responses are heterogeneous and many factors other than the pandemic seemed to affect the development of OCD symptoms. To prevent the impairment of symptoms and the development of new cases, close monitoring of patients with OCD and education of the general public is essential. Literature is still limited; thus, multinational and cross-cultural, longitudinal studies are warranted to gain further insights on this topic.
背景
2019年冠状病毒病（COVID-19）大流行及其相关限制措施可能导致心理健康恶化；强迫症（OCD）患者可能受到特别影响。本系统评价旨在调查当前大流行对被诊断为强迫症患者的影响，以及大流行是否可能影响强迫症症状的发展。
方法
2021年2月9日，我们使用美国国立医学图书馆生物医学信息学和生物技术信息中心（NCBI）的PubMed、Scopus和谷歌学术进行了系统检索。尝试使用预定义的检索词识别与强迫症和COVID-19或其他大流行相关的研究文章。纳入病例报告、临床指南、信函以及包括≥100名参与者的临床研究文章；排除综述。本系统评价遵循系统评价和Meta分析的首选报告项目（PRISMA）指南，并使用纽卡斯尔-渥太华量表评估纳入的临床研究文章的质量。
结果
共有79篇文章纳入全文评估。其中，59篇为临床研究文章，2篇为临床指南，6篇为病例报告，12篇为信函。这些研究文章考察了成年强迫症确诊患者、普通人群、孕妇、医护人员、学生、年轻人、儿童和青少年的强迫症症状。仅检索到一项关于既往大流行期间强迫症的研究。
结论
本系统评价发现，在COVID-19大流行期间，无论大流行之前是否被诊断为强迫症，人们普遍经历了强迫症症状的恶化。然而，反应是异质性的，似乎除了大流行之外，还有许多因素影响强迫症症状的发展。为防止症状加重和新病例的出现，密切监测强迫症患者并对公众进行教育至关重要。相关文献仍然有限；因此，有必要开展跨国、跨文化的纵向研究，以进一步深入了解这一主题。
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