Institut de Recherche sur la Biologie de l'Insecte, UMR CNRS 7261, Université F. Rabelais, 37200 Tours, France.
Institut de Recherche sur la Biologie de l'Insecte, UMR CNRS 7261, Université F. Rabelais, 37200 Tours, France.
Curr Opin Virol. 2017 Aug;25:41-48. doi: 10.1016/j.coviro.2017.07.002. Epub 2017 Jul 17.
In a remarkable example of convergent evolution, several parasitic wasp lineages have independently captured and maintained complex DNA virus machineries, used to transfer virulence factors. Parasitic wasps, which develop inside the larvae of their insect hosts, may inject Polydnaviruses (PDVs) or Virus-Like particles (VLPs), derived from the recurrent endogenization of several large DNA viruses. PDVs evolved from the domestication in braconid and ichneumonid wasps of viruses from different families and function as gene transfer agents. In contrast, the independent domestication of nudiviruses led to the evolution of both PDV and VLP strategies. In Venturia canescens, the endogenous nudivirus has lost the ability to encapsidate DNA, instead VLPs cargo virulence molecules of wasp origin to the parasitized host.
在趋同进化的一个显著例子中，几个寄生蜂谱系独立地捕获并维持了复杂的 DNA 病毒机制，用于转移毒力因子。寄生蜂在其昆虫宿主的幼虫体内发育，可能会注射多 DNA 病毒 (PDV) 或病毒样颗粒 (VLP)，这些病毒来源于几种大型 DNA 病毒的反复内源性化。PDV 是由不同科的病毒在 Braconid 和 Ichnemonid 黄蜂中的驯化进化而来，作为基因转移剂发挥作用。相比之下，裸病毒的独立驯化导致了 PDV 和 VLP 策略的进化。在 Venturia canescens 中，内源性裸病毒已经失去了包裹 DNA 的能力，而是将黄蜂来源的毒力分子的 VLP 货物运送到被寄生的宿主。
