Wong Kah Hie, Kam Ka Wai, Chen Li Jia, Young Alvin L
Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China.
Int J Ophthalmol. 2017 Jul 18;10(7):1154-1162. doi: 10.18240/ijo.2017.07.21. eCollection 2017.
According to World Health Organization, the global prevalence of blindness in 2010 was 39 million people, among which 4% were due to corneal opacities. Often, the sole resort for visual restoration of patients with damaged corneas is corneal transplantation. However, despite rapid developments of surgical techniques, instrumentations and immunosuppressive agents, corneal blindness remains a prevalent global health issue. This is largely due to the scarcity of good quality corneal grafts. In this review, the causes of corneal blindness, its major treatment options, and the major contributory factors of corneal graft scarcity with potential solutions are discussed.
根据世界卫生组织的数据，2010年全球盲人患病率为3900万人，其中4%是由角膜混浊所致。通常，角膜受损患者恢复视力的唯一手段是角膜移植。然而，尽管手术技术、器械和免疫抑制剂迅速发展，角膜盲仍然是一个普遍存在的全球健康问题。这主要是由于优质角膜移植物的稀缺。在这篇综述中，我们讨论了角膜盲的病因、主要治疗选择以及角膜移植物稀缺的主要促成因素和潜在解决方案。
