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无肺炎情况下以急性胆汁淤积性肝炎及其他肺外表现为特征的儿科感染

Pediatric Infection Presenting with Acute Cholestatic Hepatitis and Other Extrapulmonary Manifestations in the Absence of Pneumonia.

作者信息

Song Won Jae, Kang Ben, Lee Hwa Pyung, Cho Joongbum, Lee Hae Jeong, Choe Yon Ho

机构信息

Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, Korea.

出版信息

Pediatr Gastroenterol Hepatol Nutr. 2017 Jun;20(2):124-129. doi: 10.5223/pghn.2017.20.2.124. Epub 2017 Jun 28.

Abstract

infections mainly involve respiratory tract; however, also can manifestate other symptoms by site involved. Extrapulmonary manifestations of infection are rarely known to occur without pneumonia. Herein we report a case of a 9-year-old boy who presented with acute cholestatic hepatitis in the absence of pneumonia. Rhabdomyolysis, skin rash, and initial laboratory results suspicious of disseminated intravascular coagulopathy were also observed in this patient. infection was identified by a 4-fold increase in immunoglobulin G antibodies to between acute and convalescent sera by enzyme-linked immunosorbent assay. This is the first pediatric case in Korea of infection presenting with acute cholestatic hepatitis in the absence of pneumonia.

摘要

感染主要累及呼吸道;然而,也可根据受累部位表现出其他症状。肺部外感染表现很少在无肺炎的情况下发生。在此,我们报告一例9岁男孩,其在无肺炎的情况下出现急性胆汁淤积性肝炎。该患者还观察到横纹肌溶解、皮疹以及最初实验室结果怀疑存在弥散性血管内凝血。通过酶联免疫吸附测定法检测到急性期和恢复期血清中针对[病原体名称未给出]的免疫球蛋白G抗体增加4倍,从而确诊感染。这是韩国首例在无肺炎情况下以急性胆汁淤积性肝炎为表现的[病原体名称未给出]感染儿科病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f82b/5517379/090098e79d0e/pghn-20-124-g001.jpg

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