Bazhanov N O, Saliaev V N
Farmakol Toksikol. 1986 May-Jun;49(3):23-7.
The time of occurrence of three stages of hypothermia (mild, moderate and deep with the rectal temperature of 33, 26 and 19 degrees C, respectively) was recorded in acute experiments on rats cooled in water (7 degrees C). It was established that under normothermia aminazine exerted the hypothermic effect and rausedil (24 hrs) the hyperthermic effect. At external cooling both aminazine and rausedil (4 hrs) exhibit the antihypothermic action.
在对置于7摄氏度水中冷却的大鼠进行的急性实验中,记录了体温过低三个阶段(轻度、中度和深度,直肠温度分别为33、26和19摄氏度)的出现时间。已确定,在正常体温下,氯丙嗪发挥降温作用,而劳塞地尔(24小时)发挥升温作用。在外部冷却时,氯丙嗪和劳塞地尔(4小时)均表现出抗体温过低作用。