Huang Yun, Zhang Yuxing, Li Jianjun, Liu Gang
Department of General Surgery, Navy General Hospital, Beijing 100048, People's Republic of China.
J BUON. 2017 May-Jun;22(3):686-691.
We investigated the effectiveness of the Charlson comorbidity index (CCI) for predicting postoperative 30-day complications and long-term survival outcomes of elderly patients who underwent laparoscopic surgery for colon cancer with radical intent.
We reviewed 178 patients aged ≥70 years who underwent laparoscopic surgery for colon cancer with radical intent between January 2008 and December 2015. Patients were divided into high CCI (CCI ≥ 3; n=71) and low CCI (CCI < 3; n=107) groups for comparative analyses of differences in their short- and long-term outcomes.
Postoperative 30-day complications were more frequent in the high CCI group than in the low CCI group. Logistic regression analysis revealed that a high CCI was significantly predictive of postoperative 30-day complications. The 5-year overall survival (OS) rates were 65% and 54% for the low and high CCI groups, respectively (p=0.034) and their 5-year disease-free survival (DFS) rates were 60% and 47%, respectively (p=0.030).
CCI predicted the likelihood of postoperative 30-day complications and long-term survival outcomes of elderly patients who underwent laparoscopic surgery for colon cancer with radical intent.
我们研究了Charlson合并症指数（CCI）对于预测接受根治性腹腔镜结肠癌手术的老年患者术后30天并发症及长期生存结局的有效性。
我们回顾了2008年1月至2015年12月期间178例年龄≥70岁、接受根治性腹腔镜结肠癌手术的患者。将患者分为高CCI组（CCI≥3；n=71）和低CCI组（CCI<3；n=107），以比较分析其短期和长期结局的差异。
高CCI组术后30天并发症比低CCI组更常见。逻辑回归分析显示，高CCI显著预测术后30天并发症。低CCI组和高CCI组的5年总生存率（OS）分别为65%和54%（p=0.034），其5年无病生存率（DFS）分别为60%和47%（p=0.030）。
CCI可预测接受根治性腹腔镜结肠癌手术的老年患者术后30天并发症及长期生存结局的可能性。
