Matouskova A, Hanson B, Rösmark U
Acta Obstet Gynecol Scand Suppl. 1979;83:15-29. doi: 10.3109/00016347909157220.
Two groups, each consisting of 20 parturients, were given a continuous infusion of 0.25 per cent bupivacaine into the epidural space for pain relief, after test and loading doses. The analgesic effect was registered during labor. After delivery the course of the catheters in the epidural space was investigated radiologically. In the first group long catheters (mean 16.5 cm from the skin surface) and in the second group short catheters (mean 10.5 cm) were used. The medial approach in the epidural space was varied between the first and second lumbar interspaces. The relationship between the position of the catheter tip and the degree of analgesia was also studied. In two mothers with fetus mortuus ante partum, the spread of a radiopaque dye solution was followed during labor. Through the force of gravity and the mothers position, the spread of solution covered three segments within 30 minutes. It was concluded, that slow infusion of local anesthetic solution gives satisfactory pain relief if the catheter is inserted into the first lumbar interspace to a depth of 10--12 cm from the skin surface ending close to the Th12 level. Gradual raising of the mother from the supine to the semirecumbent position and regular change of sides during mini-infusion is important for an even spread of the analgesic solution and analgasia.
两组,每组由20名产妇组成,在给予试验剂量和负荷剂量后,通过硬膜外间隙持续输注0.25%布比卡因以缓解疼痛。在分娩过程中记录镇痛效果。分娩后,通过放射学方法研究硬膜外间隙中导管的走行。第一组使用长导管(距皮肤表面平均16.5厘米),第二组使用短导管(平均10.5厘米)。硬膜外间隙的穿刺入路在第一和第二腰椎间隙之间变化。还研究了导管尖端位置与镇痛程度之间的关系。在两名产前死胎的母亲中,在分娩过程中观察了不透X线染料溶液的扩散情况。通过重力和母亲的体位,溶液在30分钟内扩散覆盖了三个节段。得出的结论是,如果将导管插入第一腰椎间隙,从皮肤表面插入深度为10-12厘米,末端靠近胸12水平,缓慢输注局部麻醉溶液可提供满意的疼痛缓解。在微量输注过程中,逐渐将母亲从仰卧位抬高到半卧位并定期更换体位,对于镇痛溶液的均匀扩散和镇痛很重要。