不同肥胖程度患者使用胃内球囊进行体重减轻的评估。

Assessment of Weight Loss With the Intragastric Balloon in Patients With Different Degrees of Obesity.

作者信息

Nunes Gabriel C, Pajecki Denis, de Melo Maria E, Mancini Marcio C, de Cleva Roberto, Santo Marco A

机构信息

*Clinicas Hospital, Bariatric and Metabolic Surgical Unit †Clinicas Hospital, Obesity Unit, Endocrinology, University of São Paulo School of Medicine, São Paulo, Brazil.

出版信息

Surg Laparosc Endosc Percutan Tech. 2017 Aug;27(4):e83-e86. doi: 10.1097/SLE.0000000000000440.

DOI:10.1097/SLE.0000000000000440

PMID:28731953

Abstract

INTRODUCTION

The intragastric balloon (IGB) is an endoscopic device for the treatment of obesity. Best results are observed in patients who follow a dietary program but few studies have assessed the results of this treatment in patients with different degrees of obesity.

AIM

The aim of this study is to compare the efficacy of IGB in patients with different degrees of obesity.

METHOD

A total of 2002 patients with IGB were retrospectively evaluated and were divided into groups according to initial body mass index (BMI) range, as follows: group 1, 27 to 29.9 kg/m; group 2, 30 to 34.9 kg/m; group 3, 35 to 39.9 kg/m; group 4, 40 to 44.9 kg/m; group 5, ≥45 kg/m. Weight was assessed in 3 different times: before (T0), 1 month (T1), 6 months (T2), and 6 months after removal of the IGB (T3).

RESULTS

A total of 946 patients lost follow-up. Overall, 40 (3.78%) removed the device before programmed by intolerance, and 1016 patients completed the 6-month treatment. The mean weight loss was 18.9%, excess weight loss 60.1% and an BMI reduction of 6.76 points. 6 months after removal of the balloon 842 patients had continued follow-up (82.8%). At this time, weight loss was 19.84%, excess weight loss was 59.49%, and BMI reduction of 7.06 points. In all groups there was statistical difference between the times T0 and T1 and between T1 and T2 (P<0.001). There was no statistical difference between T2 and T3, in any group.

CONCLUSION

IGB provided sustained weight loss in patients who remained in dietary follow-up for 1 year.

摘要

引言

胃内球囊（IGB）是一种用于治疗肥胖症的内镜装置。在遵循饮食计划的患者中观察到了最佳效果，但很少有研究评估这种治疗方法在不同肥胖程度患者中的效果。

目的

本研究的目的是比较IGB在不同肥胖程度患者中的疗效。

方法

对总共2002例接受IGB治疗的患者进行回顾性评估，并根据初始体重指数（BMI）范围分为以下几组：第1组，27至29.9 kg/m²；第2组，30至34.9 kg/m²；第3组，35至39.9 kg/m²；第4组，40至44.9 kg/m²；第5组，≥45 kg/m²。在3个不同时间点评估体重：治疗前（T0）、1个月（T1）、6个月（T2）以及取出IGB后6个月（T3）。

结果

共有946例患者失访。总体而言，40例（3.78%）因不耐受在计划时间前取出了装置，1016例患者完成了6个月的治疗。平均体重减轻18.9%，超重减轻60.1%，BMI降低6.76个点。取出球囊6个月后，842例患者继续接受随访（82.8%）。此时，体重减轻19.84%，超重减轻59.49%，BMI降低7.06个点。在所有组中，T0与T1之间以及T1与T2之间均存在统计学差异（P<0.001）。在任何组中，T2与T3之间均无统计学差异。