Department of Surgery & Cancer, Imperial College London, London, UK.
University College Hospital, London, UK.
Dig Dis Sci. 2018 Jul;63(7):1694-1705. doi: 10.1007/s10620-018-5117-1.
Obesity is a global health problem which is on the rise and is strongly associated with the development of type 2 diabetes and other comorbidities. Bariatric surgery is now an established treatment for both these conditions, leading to impressive results in weight loss and glycemic control. More recently, we have seen the development of various endoscopic devices as potential alternatives or adjuncts to bariatric surgery. In this state-of-the-art review, we outline the current landscape of endoscopic treatments available for the management of both obesity and diabetes, including the clinical evidence supporting their use, efficacy, safety, and potential mechanisms of action.
肥胖是一个全球性的健康问题,呈上升趋势,与 2 型糖尿病和其他合并症的发展密切相关。减重手术现在是这两种疾病的既定治疗方法,在减肥和血糖控制方面取得了令人瞩目的效果。最近,我们看到各种内镜设备的发展,作为减重手术的潜在替代或辅助手段。在这篇最新综述中,我们概述了目前可用于肥胖和糖尿病管理的内镜治疗方法,包括支持其使用的临床证据、疗效、安全性以及潜在的作用机制。