Quesada J R, Gutterman J U
Lancet. 1986 Jun 28;1(8496):1466-8. doi: 10.1016/s0140-6736(86)91502-3.
Two patients with metastatic renal carcinoma who were treated with recombinant-DNA-derived alpha-interferon (rIFN alpha) had exacerbation of concomitant psoriasis, and another patient experienced onset of psoriasis during treatment with rIFN alpha. This suggests that interferons may participate in the pathophysiology of psoriasis.
两名接受重组DNA衍生的α干扰素(rIFNα)治疗的转移性肾癌患者,其伴发的银屑病病情加重,另一名患者在接受rIFNα治疗期间出现银屑病。这表明干扰素可能参与了银屑病的病理生理过程。