School of Chemical Engineering, Fuzhou University, Fuzhou 350108, People's Republic of China.
School of Chemical Engineering, Fuzhou University, Fuzhou 350108, People's Republic of China.
Carbohydr Polym. 2017 Oct 1;173:701-706. doi: 10.1016/j.carbpol.2017.06.003. Epub 2017 Jun 2.
Development of bio-based hydrogels with good mechanical properties is of great importance for their excellent biocompatibility and biodegradability. In this paper, chitosan (CS) based double network (DN) hydrogel was prepared by dissolving CS in AlCl·6HO aqueous solution instead of acetic acid solution. After dissolving acrylic amide (AM), acrylic acid (AA), N, N'-methylenebisacrylamide and 2-hydroxy-4'-(2-hydoxyethoxy)-2-methylpropiophenone were added into the CS/Al solution and the CS/PAMAA-Al DN hydrogel was prepared by UV polymerization. The hybrid physical and chemical crosslinked network hydrogels were prepared. The tensile and compression properties of CS/PAMAA-Al DN hydrogel were studied. The results showed that the CS/PAMAA-Al DN hydrogels have high toughness, stretch-ability, and excellent shape recovery properties. The CS/PAMAA-Al DN hydrogel could show the tensile strength of 0.54MPa and elongation at break of 2203.7%. These properties arise from the dynamic ionic interaction between Al and CS/PAMAA macromolecular chains.
开发具有良好机械性能的生物基水凝胶对于其优异的生物相容性和可生物降解性非常重要。本文通过将壳聚糖（CS）溶解在 AlCl·6HO 水溶液中而不是乙酸溶液中，制备了 CS 基双网络（DN）水凝胶。在溶解丙烯酰胺（AM）、丙烯酸（AA）、N，N'-亚甲基双丙烯酰胺和 2-羟基-4'-(2-羟乙氧基)-2-甲基苯丙酮后，将其加入到 CS/Al 溶液中，并通过 UV 聚合制备了 CS/PAMAA-Al DN 水凝胶。制备了混合物理和化学交联网络水凝胶。研究了 CS/PAMAA-Al DN 水凝胶的拉伸和压缩性能。结果表明，CS/PAMAA-Al DN 水凝胶具有高韧性、可拉伸性和优异的形状回复性能。CS/PAMAA-Al DN 水凝胶的拉伸强度可达 0.54MPa，断裂伸长率可达 2203.7%。这些性能源于 Al 与 CS/PAMAA 大分子链之间的动态离子相互作用。
