Department of Psychology, New York University, New York University, 6 Washington Place, New York, NY, 10003, USA.
Center for Neural Science, New York University, New York University, 6 Washington Place, New York, NY, 10003, USA.
Sci Rep. 2017 Jul 21;7(1):6188. doi: 10.1038/s41598-017-06293-x.
Although subregions of frontal and parietal cortex both contribute and coordinate to support working memory (WM) functions, their distinct contributions remain elusive. Here, we demonstrate that perturbations to topographically organized human frontal and parietal cortex during WM maintenance cause distinct but systematic distortions in WM. The nature of these distortions supports theories positing that parietal cortex mainly codes for retrospective sensory information, while frontal cortex codes for prospective action.
尽管额皮质和顶叶皮质的亚区都有助于并协调支持工作记忆 (WM) 功能,但它们的独特贡献仍难以捉摸。在这里,我们证明在 WM 维持期间对拓扑组织的人类额皮质和顶叶皮质的干扰会导致 WM 中出现明显但系统的扭曲。这些扭曲的性质支持了这样的理论,即顶叶皮质主要对回顾性感觉信息进行编码,而额皮质对前瞻性动作进行编码。