Cho Sung Yong, Park Juhyun, Yoo Sangjun, Cho Min Chul, Jeong Hyeon, Son Hwancheol
Department of Urology, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea.
Department of Urology, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea.
Urology. 2017 Oct;108:142-148. doi: 10.1016/j.urology.2017.07.012. Epub 2017 Jul 20.
To evaluate surgical outcomes of patients who underwent complete or incomplete enucleation technique during a short-term postoperative period.
Patients having intractable lower urinary tract symptoms/benign prostatic hyperplasia and prostates >30 g with obstructed pattern in the urodynamic examinations were included. They underwent transurethral resection of prostate (TUR-P), 120 W GreenLight laser high power system-photoselective vapoenucleation of prostate (HPS-PVEP), or holmium laser enucleation of prostate (HoLEP). Patients with the size of remnant prostates minus surgical defects <25 g were grouped into the completely enucleated group (group C), and others were grouped into the partially enucleated group (group P).
Mean prostate-specific antigen value was 3.5 ± 4.5 ng/mL, and mean prostate volume was 58.4 ± 31.0 mL. Complete enucleation rates in TUR-P, HPS-PVEP, and HoLEP groups were 39% (37 out of 95), 54.6% (83 out of 152), and 54.4% (31 out of 57), respectively. Complete enucleation rate of the TUR-P was significantly lower than those of the other 2 groups. Compared with group C, group P had lower maximal flow rate, higher bladder outlet obstruction index, and higher overactive bladder symptom scores. Multivariate logistic regression analyses showed that smaller prostate, presence of intravesical prostatic protrusion, HoLEP operation, and surgeons' experience were significant predictors for achieving complete enucleation of prostate. Voiding subscores of group C were significantly higher than those of group P at postoperative 12 months.
The performance of HoLEP was superior to other surgical techniques. However, HPS-PVEP with vapoenucleation showed the comparable enucleation rate with that of HoLEP. Complete enucleation was effective in maintaining outcomes of prostate resection, especially voiding subscores.
评估在术后短期内接受完全或不完全剜除术的患者的手术效果。
纳入患有顽固性下尿路症状/良性前列腺增生且前列腺重量>30 g、尿动力学检查呈梗阻型的患者。他们接受了经尿道前列腺切除术(TUR-P)、120 W绿光激光高功率系统-前列腺光选择性汽化剜除术(HPS-PVEP)或钬激光前列腺剜除术(HoLEP)。残余前列腺大小减去手术缺损<25 g的患者被归入完全剜除组(C组),其他患者被归入部分剜除组(P组)。
前列腺特异性抗原平均 值为3.5±4.5 ng/mL,前列腺平均体积为58.4±31.0 mL。TUR-P组、HPS-PVEP组和HoLEP组的完全剜除率分别为39%(95例中的37例)、54.6%(152例中的83例)和54.4%(57例中的31例)。TUR-P组的完全剜除率显著低于其他两组。与C组相比,P组的最大尿流率较低、膀胱出口梗阻指数较高且膀胱过度活动症症状评分较高。多因素逻辑回归分析显示,较小的前列腺、膀胱内前列腺突出的存在、HoLEP手术以及术者经验是实现前列腺完全剜除的重要预测因素。术后12个月时,C组的排尿子评分显著高于P组。
HoLEP的手术效果优于其他手术技术。然而,采用汽化剜除术的HPS-PVEP的剜除率与HoLEP相当。完全剜除术对于维持前列腺切除术后的效果有效,尤其是排尿子评分。