从的黎波里利比亚医院分离的耐甲氧西林金黄色葡萄球菌 spa 型别和 pvl 基因的鉴定。
Spa typing and identification of pvl genes of meticillin-resistant Staphylococcus aureus isolated from a Libyan hospital in Tripoli.
机构信息
Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, P.O. Box 13662, University of Tripoli, Libya.
Department of Veterinary Medicine, Danish Medicines Agency, DK-2300, Copenhagen South, Denmark.
出版信息
J Glob Antimicrob Resist. 2017 Sep;10:179-181. doi: 10.1016/j.jgar.2017.06.004. Epub 2017 Jul 19.
OBJECTIVES
The purpose of the study was to investigate the molecular characteristics of meticillin-resistant Staphylococcus aureus (MRSA) isolated from clinical sources in Tripoli, Libya.
METHODS
A total of 95 MRSA strains collected at the Tripoli medical Centre were investigated by spa typing and identification of the Panton-Valentine Leukocidin (pvl) genes.
RESULTS
A total of 26 spa types were characterized and distributed among nine clonal complexes; CC5 (n=32), CC80 (n=18), CC8 (n=17) and CC22 (n=12) were the most prevalent clonal complexes. In total, 34% of the isolates were positive for PVL.
CONCLUSIONS
This study demonstrated the presence of CA-MRSA and pvl positive strains in hospital settings and underlines the importance of using molecular typing to investigate the epidemiology of MRSA. Preventative measures and surveillance systems are needed to control and minimize the spread of MRSA in the Libyan health care system.
目的
本研究旨在调查利比亚的黎波里临床来源的耐甲氧西林金黄色葡萄球菌（MRSA）的分子特征。
方法
对的黎波里医疗中心采集的 95 株 MRSA 菌株进行 spa 分型和杀白细胞素基因（pvl）鉴定。
结果
共鉴定出 26 种 spa 型，分布于 9 个克隆群；CC5（n=32）、CC80（n=18）、CC8（n=17）和 CC22（n=12）是最常见的克隆群。总共有 34%的分离株为 PVL 阳性。
结论
本研究表明，医院环境中存在 CA-MRSA 和 pvl 阳性菌株，这强调了使用分子分型来调查 MRSA 流行病学的重要性。需要采取预防措施和监测系统来控制和最大限度地减少 MRSA 在利比亚医疗保健系统中的传播。
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