Wang Timothy Y, Nayar Gautam, Brown Christopher R, Pimenta Luiz, Karikari Isaac O, Isaacs Robert E
Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina, USA.
Department of Orthopaedic Surgery, Duke University Medical Center, Raleigh, North Carolina, USA.
World Neurosurg. 2017 Oct;106:819-826. doi: 10.1016/j.wneu.2017.07.045. Epub 2017 Jul 19.
Although extreme lateral interbody fusion (XLIF) largely provides successful indirect decompression, some patients have recurrent same-level pain and functional disability. Identifying risk factors for this failure would facilitate better patient selection and improve outcomes. The aim of this study is to identify preoperative radiographic risk factors for failure of XLIF.
Patients undergoing XLIF were prospectively enrolled by 3 surgeons at 3 separate institutions. Radiographic variables measured included (1) anterior and posterior disc height, (2) foramen height and area, (3) central canal diameter, (4) central canal area, (5) right and left subarticular diameters, (6) facet arthropathy grade, and (7) presence of bony lateral recess stenosis. Patients failed indirect decompression if Oswestry Disability Index (ODI) scores did not improve by 20 points or revision surgery was required within 6 months postoperatively. Univariate and multivariate analyses were performed to identify radiographic predictors of failure of indirect decompression.
Of the 45 patients (age 65.6 ± 10.5 years; 14 male) involving 101 spinal levels included in this study, 13 (29%) failed indirect decompression. From univariate analysis, these patients had significantly smaller central canal diameter, foraminal height, and disc height (P < 0.05). In multivariate analysis of these parameters and those trending toward significance, bony lateral recess stenosis was the only significant independent predictor for failure of indirect decompression (coefficient, 0.55 [0.24-0.85]; P < 0.001).
Bony lateral recess stenosis is an independent predictor for failure to achieve adequate spinal decompression via XLIF and thus may benefit from undergoing direct decompression.
尽管极外侧椎间融合术(XLIF)在很大程度上能成功实现间接减压,但仍有一些患者出现同节段复发性疼痛和功能障碍。识别导致这种手术失败的风险因素将有助于更好地选择患者并改善治疗效果。本研究的目的是确定XLIF手术失败的术前影像学风险因素。
3名外科医生在3个不同机构前瞻性纳入接受XLIF手术的患者。测量的影像学变量包括:(1)椎间盘前后高度;(2)椎间孔高度和面积;(3)中央管直径;(4)中央管面积;(5)左右关节突下直径;(6)小关节病分级;(7)是否存在骨性侧隐窝狭窄。如果Oswestry功能障碍指数(ODI)评分改善未达20分或术后6个月内需要翻修手术,则认为间接减压失败。进行单因素和多因素分析以确定间接减压失败的影像学预测因素。
本研究纳入的45例患者(年龄65.6±10.5岁;男性14例)共101个脊柱节段,其中13例(29%)间接减压失败。单因素分析显示,这些患者的中央管直径、椎间孔高度和椎间盘高度明显更小(P<0.05)。对这些参数以及有显著趋势的参数进行多因素分析时,骨性侧隐窝狭窄是间接减压失败的唯一显著独立预测因素(系数为0.55[0.24 - 0.85];P<0.001)。
骨性侧隐窝狭窄是XLIF手术未能实现充分脊髓减压的独立预测因素,因此可能受益于直接减压手术。