Feldmann Joerg, Raab Andrea, Krupp Eva M
Trace Element Speciation Laboratory, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen, AB24 3UE, UK.
Anal Bioanal Chem. 2018 Jan;410(3):661-667. doi: 10.1007/s00216-017-0502-8. Epub 2017 Jul 22.
This article is aimed at researchers interested in organic molecules which contain a heteroatom but who have never considered using inductively coupled plasma mass spectrometry (ICPMS) or who have used ICPMS for years and developed numerous methods for analysis of target elemental species. We try to illustrate (1) that ICPMS has been very useful for speciation analysis of metal(loid) target species and that there is now a trend to replace the costly detector with cheaper detection systems for routine target analysis, and (2) that ICPMS has been used and will be used even more in the future for non-targeted analysis of elements which are not normally associated with ICPMS analysis, such as non-metals such as sulfur, phosphorus, chlorine and fluorine. Graphical Abstract Starting with HPLC-ICPMS for non-targeted analysis of heteroatom containing molecules, once target molecule is identified alternative detectors can be used for routine measurements.
本文面向对含杂原子有机分子感兴趣的研究人员，这些研究人员从未考虑过使用电感耦合等离子体质谱法（ICPMS），或者已经使用ICPMS多年并开发了许多用于分析目标元素种类的方法。我们试图说明：（1）ICPMS在金属（类金属）目标物种的形态分析中非常有用，目前有一种趋势，即用更便宜的检测系统取代昂贵的检测器用于常规目标分析；（2）ICPMS已经用于并且未来将更多地用于对通常与ICPMS分析无关的元素进行非靶向分析，例如硫、磷、氯和氟等非金属元素。图形摘要 从用于含杂原子分子非靶向分析的HPLC-ICPMS开始，一旦确定目标分子，就可以使用替代检测器进行常规测量。
