Suppr超能文献

秘鲁城郊地区吸烟率较低:一项基于人群的自我报告和尿可替宁烟草使用研究结果

Low cigarette smoking prevalence in peri-urban Peru: results from a population-based study of tobacco use by self-report and urine cotinine.

作者信息

Morgan Brooks W, Leifheit Kathryn M, Romero Karina M, Gilman Robert H, Bernabe-Ortiz Antonio, Miranda J Jaime, Feldman Harold I, Lima John J, Checkley William

机构信息

Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St, Baltimore, Maryland 21205 USA.

Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 N. Wolfe St, Baltimore, Maryland 21205 USA.

出版信息

Tob Induc Dis. 2017 Jul 21;15:32. doi: 10.1186/s12971-017-0137-8. eCollection 2017.

Abstract

BACKGROUND

A recent study found lower self-reported prevalence of tobacco smoking in a peri-urban area of Lima, Peru than previously reported in urban samples. These regions encompass substantial proportions of Peru's population - ones at greater risk of disease due to reduced healthcare access - but have been less often studied. We validate low smoking prevalence with urine cotinine and characterize chronic disease and lung function outcomes between non-, occasional, and daily smokers.

METHODS

Data are from the CRONICAS Cohort Study, a population-based longitudinal study in four low-resource Peruvian settings, which began in 2010. Of a baseline cohort of 2978 adults, we prospectively followed 2583 (87%) to determine prevalence of chronic illness.

RESULTS

In a baseline sub-sample of 382 participants, median adjusted cotinine was 0.0 mcg/mg (IQR 0-0) for both self-reported non-smokers and occasional smokers compared to 172.3 mcg/mg (IQR 0-709.2) for daily smokers. Creatinine-adjusted cotinine validated daily smoking prevalence of 4.7% at a cutoff of 100 mcg/mg. Kappa statistic for daily smoking and creatinine- adjusted cotinine ≥100 mcg/mg was 0.65 (95% CI 0.47, 0.83), indicating substantial agreement. At baseline, we found 3.3% daily and 8.9% occasional smoking by self-report for the full cohort. Follow-up indicated little difference in chronic disease prevalence between groups. Daily smokers trended toward having a greater decline in FVC (-1%; 95% CI -2.9, 0.8) and FEV (-1.3%; 95% CI -3.2, 0.6) over 40 months when compared to non-smokers, whereas the decline in lung function for occasional smokers was similar compared to non-smokers (-0.2% FVC; 95% CI -1.5, 1.0) and (0% FEV; 95% CI -1.3, 1.3).

CONCLUSIONS

Our data places Peru within a previously-described pattern of smoking found in much of Latin America, favoring occasional over daily smoking and low cigarette consumption. We determine that there are not significant differences between smoking groups concerning chronic disease outcomes. We favor distinguishing between daily and occasional smokers in order to accurately characterize these low-use populations.

摘要

背景

最近一项研究发现,秘鲁利马市周边地区自我报告的吸烟率低于此前城市样本中的报告水平。这些地区涵盖了秘鲁相当大比例的人口——由于获得医疗保健的机会减少,他们患疾病的风险更高——但此前对这些地区的研究较少。我们通过尿可替宁验证了低吸烟率,并对非吸烟者、偶尔吸烟者和每日吸烟者的慢性病及肺功能结果进行了特征描述。

方法

数据来自CRONICAS队列研究,这是一项于2010年在秘鲁四个资源匮乏地区开展的基于人群的纵向研究。在2978名成年人的基线队列中,我们对2583人(87%)进行了前瞻性随访,以确定慢性病的患病率。

结果

在382名参与者的基线子样本中,自我报告的非吸烟者和偶尔吸烟者的校正后可替宁中位数均为0.0微克/毫克(四分位间距0 - 0),而每日吸烟者为172.3微克/毫克(四分位间距0 - 709.2)。肌酐校正后的可替宁在阈值为100微克/毫克时验证了每日吸烟率为4.7%。每日吸烟与肌酐校正后可替宁≥100微克/毫克的kappa统计量为0.65(95%置信区间0.47, 0.83),表明一致性较高。在基线时,我们通过自我报告发现整个队列中每日吸烟率为3.3%,偶尔吸烟率为8.9%。随访表明,各组之间慢性病患病率差异不大。与非吸烟者相比,每日吸烟者在40个月内用力肺活量(FVC)下降趋势更大(-1%;95%置信区间-2.9, 0.8),第一秒用力呼气容积(FEV)下降趋势更大(-1.3%;95%置信区间-3.2, 0.6),而偶尔吸烟者的肺功能下降与非吸烟者相似(FVC下降-0.2%;95%置信区间-1.5, 1.0)以及(FEV下降0%;95%置信区间-1.3, 1.3)。

结论

我们的数据表明,秘鲁符合此前在拉丁美洲大部分地区发现的吸烟模式,即倾向于偶尔吸烟而非每日吸烟,且香烟消费量较低。我们确定吸烟组之间在慢性病结果方面没有显著差异。我们主张区分每日吸烟者和偶尔吸烟者,以便准确描述这些低吸烟人群的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0ad/5521105/ad5c1e133285/12971_2017_137_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验