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二手烟、高血压与心血管风险:来自秘鲁的研究发现。

Second-hand smoking, hypertension and cardiovascular risk: findings from Peru.

机构信息

CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.

Universidad Científica del Sur, Lima, Peru.

出版信息

BMC Cardiovasc Disord. 2021 Dec 3;21(1):576. doi: 10.1186/s12872-021-02410-x.

Abstract

BACKGROUND

Second-hand smoking has not been detailedly studied in Peru, where smoking is prohibited in all indoor workplaces, public places, and public transportation. Second-hand smoke exposure may occur at home or any other places. This study aimed to estimate the prevalence of second-hand smoking and assess its association with hypertension and cardiovascular risk in Peru.

MATERIALS AND METHODS

Secondary analysis of a nationally-representative population-based survey including individuals aged 18-59 years. There were two outcomes: hypertension and 10-year cardiovascular risk using the Framingham and the 2019 World Health Organization (WHO) risk scores. The exposure was self-reported second-hand smoking during the 7 days before the survey. The association between second-hand smoking and hypertension was quantified with Poisson models reporting prevalence ratio (PR) and 95% confidence interval (95% CI); the association between second-hand smoking and cardiovascular risk was quantified with linear regressions reporting coefficients and their 95% CI.

RESULTS

Data from 897 individuals, mean age: 38.2 (SD: 11.8) years, and 499 (55.7%) females, were analyzed, with 8.7% subjects reporting second-hand smoking at home and 8.3% at work or any other place. Thus, 144 (15.5%; 95% CI: 12.8%-18.6%) subjects reported any second-hand smoking. In multivariable model second-hand smoking was associated with hypertension (PR = 2.42; 95% CI: 1.25-4.67), and with 1.2% higher Framingham cardiovascular risk, and 0.2% higher 2019 WHO risk score.

CONCLUSIONS

There is an association between second-hand smoking and hypertension as well as with cardiovascular risk, and 15% of adults reported second-hand smoke exposure overall with half of them exposed at home. There is a need to guarantee smoking-free places to reduce cardiovascular risk.

摘要

背景

在秘鲁,所有室内工作场所、公共场所和公共交通工具都禁止吸烟,因此二手烟问题尚未得到详细研究。二手烟暴露可能发生在家里或其他任何地方。本研究旨在评估秘鲁的二手烟暴露情况及其与高血压和心血管风险的关系。

材料和方法

对一项全国代表性的基于人群的调查进行二次分析,纳入年龄在 18-59 岁的个体。有两个结果:高血压和使用弗雷明汉和 2019 年世界卫生组织(WHO)风险评分的 10 年心血管风险。暴露情况为调查前 7 天内的自我报告二手烟暴露。用泊松模型报告患病率比(PR)和 95%置信区间(95%CI)来量化二手烟暴露与高血压之间的关系;用线性回归报告系数及其 95%CI 来量化二手烟暴露与心血管风险之间的关系。

结果

分析了 897 名平均年龄为 38.2(标准差:11.8)岁的个体,其中 499 名(55.7%)为女性,有 8.7%的受试者报告在家中接触二手烟,8.3%的受试者在工作场所或其他地方接触二手烟。因此,有 144 名(15.5%;95%CI:12.8%-18.6%)受试者报告接触任何二手烟。在多变量模型中,二手烟暴露与高血压(PR=2.42;95%CI:1.25-4.67)相关,且与弗雷明汉心血管风险增加 1.2%和 2019 年 WHO 风险评分增加 0.2%相关。

结论

二手烟暴露与高血压以及心血管风险之间存在关联,总体上有 15%的成年人报告接触二手烟,其中一半人在家中接触二手烟。需要保证无烟场所以降低心血管风险。

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