Health Services Research Unit, Department of Community Medicine, University of Tromsø, 9037, Tromsø, Norway.
Int J Public Health. 2018 Mar;63(2):181-192. doi: 10.1007/s00038-017-1021-2. Epub 2017 Jul 24.
The aim of this study was to (1) identify the influence of childhood socioeconomic status (CSES) on five chronic conditions: asthma, bronchitis, hypothyroid, migraine, and psychiatric disorders in later life; (2) determine the mediating role of childhood abuse (CA) in these associations, and (3) quantify recall bias due to respondent's mental health in these associations.
10,325 men and women from the Tromsø Study were followed for 13 years, and Poisson regression models were used.
Low CSES was associated with a 16-23% higher risk of chronic conditions, and CA was associated with a 16-58% higher risk of chronic conditions (p < 0.05). A minor proportion of the association between CSES and CA (3.98%, p < 0.05); CSES and chronic conditions (5.54-8.71%, p < 0.05); and CA and chronic conditions (9.51-19.52%, p < 0.05), were driven by recall bias due to the respondent's mental health. CA mediated the association between CSES and chronic conditions (9.58-25.06%, p < 0.05).
Low CSES and CA are associated with higher risk of chronic conditions in later life. A minor proportion of these associations are driven by recall bias.
本研究旨在：(1) 确定童年社会经济地位（CSES）对五种慢性疾病（哮喘、支气管炎、甲状腺功能减退、偏头痛和精神障碍）的影响；(2) 确定童年期虐待（CA）在这些关联中的中介作用；(3) 量化由于受访者心理健康而导致的这些关联中的回忆偏差。
10325 名来自特罗姆瑟研究的男性和女性随访了 13 年，使用泊松回归模型。
低 CSES 与慢性疾病的风险增加 16-23%相关，CA 与慢性疾病的风险增加 16-58%相关（p<0.05）。CSES 与 CA（3.98%，p<0.05）、CSES 与慢性疾病（5.54-8.71%，p<0.05）和 CA 与慢性疾病（9.51-19.52%，p<0.05）之间的关联有一小部分是由受访者心理健康导致的回忆偏差驱动的。CA 介导了 CSES 与慢性疾病之间的关联（9.58-25.06%，p<0.05）。
低 CSES 和 CA 与晚年慢性疾病的风险增加有关。这些关联中有一小部分是由回忆偏差引起的。
