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急诊科糖尿病患者的哨点就诊作为高血糖急症的警示信号。

Sentinel visits in emergency department patients with diabetes mellitus as a warning sign for hyperglycemic emergencies.

作者信息

Yan Justin W, Gushulak Katherine M, Columbus Melanie P, Hamelin Alexandra L, Wells George A, Stiell Ian G

机构信息

*Division of Emergency Medicine,Department of Medicine,London Health Sciences Centre,London,ON.

‡Department of Emergency Medicine,University of Ottawa,Ottawa,ON.

出版信息

CJEM. 2018 Mar;20(2):230-237. doi: 10.1017/cem.2017.338. Epub 2017 Jul 25.

Abstract

OBJECTIVES

Patients with poorly controlled diabetes mellitus may have a sentinel emergency department (ED) visit for a precipitating condition prior to presenting for a hyperglycemic emergency, such as diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS). This study's objective was to describe the epidemiology and outcomes of patients with a sentinel ED visit prior to their hyperglycemic emergency visit.

METHODS

This was a 1-year health records review of patients≥18 years old presenting to one of four tertiary care EDs with a discharge diagnosis of hyperglycemia, DKA, or HHS. Trained research personnel collected data on patient characteristics, management, disposition, and determined whether patients came to the ED within the 14 days prior to their hyperglycemia visit. Descriptive statistics were used to summarize the data.

RESULTS

Of 833 visits for hyperglycemia, 142 (17.0%; 95% CI: 14.5% to 19.6%) had a sentinel ED presentation within the preceding 14 days. Mean (SD) age was 50.5 (19.0) years and 54.4% were male; 104 (73.2%) were discharged from this initial visit, and 98/104 (94.2%) were discharged either without their glucose checked or with an elevated blood glucose (>11.0 mmol/L). Of the sentinel visits, 93 (65.5%) were for hyperglycemia and 22 (15.5%) for infection. Upon returning to the ED, 61/142 (43.0%) were admitted for severe hyperglycemia, DKA, or HHS.

CONCLUSION

In this unique ED-based study, diabetic patients with a sentinel ED visit often returned and required subsequent admission for hyperglycemia. Clinicians should be vigilant in checking blood glucose and provide clear discharge instructions for follow-up and glucose management to prevent further hyperglycemic emergencies from occurring.

摘要

目的

糖尿病控制不佳的患者在出现高血糖急症(如糖尿病酮症酸中毒(DKA)或高渗高血糖状态(HHS))之前,可能会因某种促发状况而在急诊室(ED)进行首次就诊。本研究的目的是描述在高血糖急症就诊之前进行急诊室首次就诊的患者的流行病学特征和结局。

方法

这是一项为期1年的健康记录回顾研究,研究对象为年龄≥18岁、前往四家三级医疗急诊室之一就诊且出院诊断为高血糖、DKA或HHS的患者。经过培训的研究人员收集了患者特征、治疗、处置等数据,并确定患者是否在高血糖就诊前14天内到过急诊室。采用描述性统计方法对数据进行总结。

结果

在833次高血糖就诊中,142次(17.0%;95%置信区间:14.5%至19.6%)在之前14天内有过急诊室首次就诊。平均(标准差)年龄为50.5(19.0)岁,54.4%为男性;104例(73.2%)在首次就诊后出院,其中98/104例(94.2%)出院时未检查血糖或血糖升高(>11.0 mmol/L)。在首次就诊中,93次(65.5%)是因为高血糖,22次(15.5%)是因为感染。再次回到急诊室时,61/142例(43.0%)因严重高血糖、DKA或HHS而入院。

结论

在这项基于急诊室的独特研究中,有过急诊室首次就诊的糖尿病患者经常复诊,且后续因高血糖需要入院治疗。临床医生应警惕检查血糖,并提供明确的出院随访和血糖管理指导,以防止进一步发生高血糖急症。

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