Yan Justin W, Van Aarsen Kristine, Thorne Joe, Karp Igor, Spaic Tamara, Liu Selina L, Woods Nicolas, Stiell Ian G
Division of Emergency Medicine, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Lawson Health Research Institute, London, ON, Canada.
CJEM. 2025 Apr 25. doi: 10.1007/s43678-025-00913-6.
Previous retrospective studies have demonstrated that patients with sub-optimally controlled diabetes have higher healthcare resource utilization in emergency department (ED) management of hyperglycemia compared to those with good glycemic control. This study's objective was to prospectively describe 30-day outcomes including return visits and hospitalizations after an initial ED visit for hyperglycemia.
We conducted a multicenter prospective cohort study of adults ≥ 18 years at four Ontario academic EDs diagnosed with hyperglycemia, diabetic ketoacidosis, or hyperosmolar hyperglycemic state. The primary outcome was an unplanned repeat ED visit for hyperglycemia within 30 days of index visit. We conducted telephone follow-up at 14 and 30 days to determine additional outcomes. Data were summarized using descriptive statistics.
There were 657 ED visits for hyperglycemia representing 594 unique patients. Mean (SD) age was 52.0 (18.2) years, 53.2% were male. Within 30 days, 96 (14.7%) had a return ED visit for hyperglycemia, 49 (7.5%) were hospitalized, and 4 (0.6%) died. We were able to contact 383 (58.3%) patients by telephone at 14 days and 275 (41.9%) at 30 days. Of these, 68.3% self-identified as Caucasian/White, while 6.3% were Indigenous. 44.9% reported an annual household income below $50,000. 29.1% of working patients took time off following their index visit.
This prospective study describes 30-day outcomes and healthcare utilization of ED patients presenting for hyperglycemia. ED clinicians should be aware of the potential for subsequent healthcare utilization and risk for readmission and intervene as appropriate to reduce adverse outcomes in patients with diabetes presenting with hyperglycemia.
既往回顾性研究表明,与血糖控制良好的患者相比,糖尿病控制欠佳的患者在急诊科(ED)处理高血糖时医疗资源利用率更高。本研究的目的是前瞻性描述初次ED就诊高血糖后30天的结局,包括复诊和住院情况。
我们在安大略省的四家学术性ED对18岁及以上诊断为高血糖、糖尿病酮症酸中毒或高渗高血糖状态的成年人进行了一项多中心前瞻性队列研究。主要结局是在首次就诊后30天内因高血糖进行的非计划再次ED就诊。我们在14天和30天时进行电话随访以确定其他结局。数据采用描述性统计进行总结。
共有657次高血糖的ED就诊,代表594名不同患者。平均(标准差)年龄为52.0(18.2)岁,53.2%为男性。在30天内,96例(14.7%)因高血糖再次到ED就诊,49例(7.5%)住院,4例(0.6%)死亡。我们在14天时能够通过电话联系到383例(58.3%)患者,在30天时联系到275例(41.9%)患者。其中,68.3%自我认定为白种人/白人,而6.3%为原住民。44.9%报告家庭年收入低于50,000美元。29.1%的在职患者在首次就诊后请假。
这项前瞻性研究描述了因高血糖就诊的ED患者的30天结局和医疗利用情况。ED临床医生应意识到后续医疗利用的可能性和再入院风险,并酌情进行干预,以减少糖尿病合并高血糖患者的不良结局。