Dionne Janis M, Flynn Joseph T
Department of Pediatrics, Division of Nephrology, University of British Columbia, BC Children's Hospital, Vancouver, Canada.
Department of Pediatrics, Division of Nephrology, University of Washington, Seattle Children's Hospital, Washington, USA.
Arch Dis Child. 2017 Dec;102(12):1176-1179. doi: 10.1136/archdischild-2015-309740. Epub 2017 Jul 24.
Blood pressure is considered a vital sign, as values too low or too high can be related with serious morbidity and mortality. In neonates, normal blood pressure values undergo rapid changes, especially in premature infants, making the recognition of abnormal blood pressures more challenging. Severe hypertension can occur in neonates and infants and is a medical emergency, often manifesting with congestive heart failure or other life-threatening complications. The cause or risk factors for the hypertension can usually be identified and may guide management. Most classes of antihypertensive medications have been used in the neonatal population. For severe hypertension, intravenous short-acting medications are preferred for a controlled reduction of blood pressure. In this article, we focus on identification, aetiology and management of severe hypertension in the newborn.
血压被视为一项生命体征,因为血压值过低或过高都可能与严重的发病率和死亡率相关。在新生儿中,正常血压值会迅速变化,尤其是早产儿,这使得识别异常血压更具挑战性。严重高血压可发生于新生儿和婴儿,属于医疗急症,常表现为充血性心力衰竭或其他危及生命的并发症。高血压的病因或风险因素通常可以确定,这可能有助于指导治疗。大多数种类的抗高血压药物都已应用于新生儿群体。对于严重高血压,首选静脉注射短效药物以控制血压降低。在本文中,我们重点关注新生儿严重高血压的识别、病因及治疗。