Sengoku K, Ishikawa M, Kasamo M, Yamashita K, Shimizu T
Int J Gynaecol Obstet. 1986 Feb;24(1):21-5. doi: 10.1016/0020-7292(86)90019-6.
The accuracy of ultrasound as a means of monitoring follicular development and ovulation detection was studied in 31 infertile women. The follicular diameter measured by ultrasound correlated well actual diameter found during laparotomy (r = 0.88), and estradiol-17 beta (E2) and progesterone in follicular fluid aspirated from large follicles (greater than or equal to 16 mm) indicated high levels. Furthermore, in 23 out of the 55 cycles, ultrasound examinations demonstrated free fluid in cul-de-sac at ovulation, and concentrations of E2 and progesterone (P) in peritoneal fluid by the puncture of cul-de-sac dramatically increased after ovulation. We suggested that ultrasound monitoring provided a reliable measure of follicular growth and prediction of ovulation, and a combined use of ultrasound and puncture of cul-de-sac could be developed into a new tool for the study of the mechanism of human ovulation.
在31名不孕妇女中研究了超声作为监测卵泡发育和排卵检测手段的准确性。超声测量的卵泡直径与剖腹手术中发现的实际直径相关性良好（r = 0.88），从大卵泡（大于或等于16毫米）抽吸的卵泡液中的雌二醇-17β（E2）和孕酮水平较高。此外，在55个周期中的23个周期中，超声检查显示排卵时直肠子宫陷凹有游离液，排卵后通过直肠子宫陷凹穿刺获得的腹腔液中E2和孕酮（P）浓度显著增加。我们认为超声监测为卵泡生长和排卵预测提供了可靠的测量方法，超声与直肠子宫陷凹穿刺的联合应用可发展成为研究人类排卵机制的新工具。
