10赫兹短周期全身振动对大鼠血液生物标志物的影响
EFFECT OF A SHORT PERIOD WHOLE BODY VIBRATION WITH 10 HZ ON BLOOD BIOMARKERS IN RATS.
作者信息
Monteiro Milena de Oliveira Bravo, de Sá-Caputo Danúbia da Cunha, Moreira-Marconi Eloá, Frederico Éric Heleno Freire Ferreira, de Sousa-Gonçalves Cintia Renata, Bernardo Luciana Camargo, Guimarães Carlos Alberto Sampaio, Bernardo-Filho Mario
机构信息
Laboratório de vibrações mecânicas e práticas integrativas e complementares - LAVIMPIC, Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Programa de Pós-Graduação em Fisiopatologia Clínica e Experimental, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
出版信息
Afr J Tradit Complement Altern Med. 2017 Jul 7;14(4 Suppl):11-18. doi: 10.21010/ajtcam.v14i4S.2. eCollection 2017.
BACKGROUND
Exposure to whole body vibration exercises (WBVE), besides some biological effects, causes alterations in the concentration of some blood biomarkers. The aim of this study is to evaluate the action of vibration (10 Hz) of WBVE on the concentration of blood biomarkers in Wistar rats.
MATERIALS AND METHODS
Wistar rats were divided in 2 groups. The experimental group (EG) was subjected to vibrations of 10Hz (one min per day, one week, total time of seven min), while the control group (CG) has not experienced vibration. Samples of whole blood were drawn for biochemical analysis of the concentration of total cholesterol, triglycerides, HDL, LDL, VLDL, glucose, CPK, albumin, alkaline phosphates, TGP, TGO, γGT, lipase, amylase, urea and creatinine.
RESULTS
White blood cell count and a platelet-hemogram were also performed. Significant (p<0.05) increase in TGP, TGO and white blood cells and decrease in LDL concentration was found after exposure of 10Hz mechanical vibration.
CONCLUSION
Although these findings were obtained with rats, they might contribute to try to understand better these mechanisms that occur following exposure to a frequency of 10Hz.
背景
全身振动训练（WBVE）除了产生一些生物学效应外，还会导致某些血液生物标志物浓度的改变。本研究的目的是评估WBVE的振动（10Hz）对Wistar大鼠血液生物标志物浓度的作用。
材料与方法
将Wistar大鼠分为2组。实验组（EG）接受10Hz的振动（每天1分钟，共1周，总时长7分钟），而对照组（CG）未经历振动。采集全血样本用于分析总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白、极低密度脂蛋白、葡萄糖、肌酸磷酸激酶、白蛋白、碱性磷酸酶、谷丙转氨酶、谷草转氨酶、γ-谷氨酰转肽酶、脂肪酶、淀粉酶、尿素和肌酐的浓度。
结果
还进行了白细胞计数和血小板血细胞计数。暴露于10Hz机械振动后，谷丙转氨酶、谷草转氨酶和白细胞显著增加（p<0.05），低密度脂蛋白浓度降低。
结论
尽管这些发现是在大鼠身上获得的，但它们可能有助于更好地理解暴露于10Hz频率后发生的这些机制。
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